Suicidal ideation can be described as compulsive thoughts or urges regarding suicide. These thoughts and desires range in intensity from fleeting thoughts to an intense fixation which is usually accompanied by severe depression. This effect can be a manifestation of a number of things including adverse reactions to certain substances, mental illness, traumatic life events, and interpersonal problems. It creates a predisposition to other self-destructive behaviors such as self-harm and drug abuse and, if left unresolved, can eventually lead to attempts of suicide.
The most common substance associated with this component are various antidepressants of the selective serotonin reuptake inhibitor class.