Responsible drug use

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Responsible drug use (also known as harm reduction) refers to a broad set of principles and practices that can be applied to the activity of psychoactive substance use for the purpose of maximizing its benefits and minimizing its negative impacts. The harm reduction approach follows from the acknowledgement that psychoactive substance use is an inherently high-risk activity that unavoidably entails the possibility of injury, addiction, and death. Therefore, the best thing one can do (outside of avoiding it entirely) is to take appropriate measures to mitigate its harms.

Recreational substance use can be viewed similarly to other risky-but-beneficial activities like driving a car, skiing, skydiving, surfing, or mountain climbing. The risks of these activities are innate but can be minimized by using caution and common sense. Therefore, individuals are solely responsible for ensuring they are doing adequate research and taking the appropriate precautions to ensure reasonably safe and enjoyable experiences for themselves and others.

Examples of general harm reduction advice include avoiding hazardous situations, excessive doses, and hazardous combinations of substances; avoiding injection; and not using substances at the same time as activities that require a sober state, such as driving or operating machinery.

This article is dedicated to providing information on the variety of factors that should be considered before choosing to experiment with psychoactive substances. The first part concerns harm reduction tactics for all substances while the bottom half focuses exclusively on hallucinogens.


Recovery position

Reagent testing kits

Dangerous combinations




This advice below is exclusively for hallucinogens such as psychedelics, dissociatives, and deliriants.


State of mind

Bodily state

Trip sitters


Aborting trips

See also

External links


  1. Erowid Psychoactive Vaults: Dose |
  2. How big is a milligram? (Ask Erowid) |
  3. The Importance of Measured Doses by Fire Erowid & Spoon |
  4. American Weigh Scales, Inc Gemini-20 User Manual |
  5. 3-MeO-PCP (Tripsit) |
  6. Liquid Measurement Technique by Zam (Erowid) |
  7. Erowid. "25I-NBOMe (2C-I-NBOMe) Fatalities / Deaths". Drug Website. Erowid. Retrieved February 28, 2016. 
  8. Hastings, Deborah (May 6, 2013). "New drug N-bomb hits the street, terrifying parents, troubling cops". New York Daily News. Retrieved May 7, 2013. 
  9. Feehan, Conor (January 21, 2016). "Powerful N-Bomb drug - responsible for spate of deaths internationally - responsible for hospitalisation of six in Cork". Irish Independent. Retrieved January 22, 2016. 
  10. Iversen, Les (May 29, 2013). "Temporary Class Drug Order Report on 5-6APB and NBOMe compounds" (PDF). Advisory Council on the Misuse of Drugs. Gov.Uk. Retrieved June 16, 2013. 
  11. Iversen, Les (May 29, 2013). "Temporary Class Drug Order Report on 5-6APB and NBOMe compounds" (PDF). Advisory Council on the Misuse of Drugs. Gov.Uk. p. 14. Retrieved June 16, 2013.