Dehydration

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Dehydration can be defined as any excessive loss of bodily water within a living organism which results in an accompanying disruption of metabolic processes. Besides an uncomfortably dry mouth and feelings of general thirstiness, symptoms of dehydration may include headaches, decreased blood pressure (hypotension), and dizziness or fainting when standing up. Untreated dehydration generally results in delirium, unconsciousness, swelling of the tongue, and (in extreme cases) death.

In relation to the consumption of psychoactive substances, mild dehydration is common under the influence of many different drugs, particularly stimulants. At moderate levels, this can be generally described as a sense of consistent and uncomfortable thirst throughout the duration of the experience which necessitates sipping at a drink to maintain fluid levels and to avoid an uncomfortably dry mouth. At extreme levels (which generally only occur with the use of deliriants), these experiences of dehydration become so powerful that one may find themselves with painfully dry eyes and mucus membranes, rendering them incapable of swallowing due to excessive and unquenchable thirst.

Water intoxication

It's important to note that regardless of how dehydrated one may become under the influence of any substance, careful effort and consideration should always be put into ensuring that one does not drink water excessively as it can result in a state known as water intoxication. This can be potentially fatal and is classed as a disturbance in brain functions that results when the normal balance of electrolytes in the body is pushed outside of safe limits by over-hydration. Although extremely rare, there have been a few notable deaths which were clearly triggered by the excessive overconsumption of water under the influence of drug-induced dehydration. The average toxic dosage of water in a human being is roughly ten litres, however, this can be easily avoided by simply sipping at water and making a conscious effort to not drink unnecessarily large amounts.

Psychoactive substances

Compounds within our psychoactive substance index which may cause this effect include:


Experience reports

Anecdotal reports which describe this effect within our experience index include:

See also