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Delirium can be described as a general decrease within various aspects of one's normal levels of cognitive functioning. This typically includes fluctuating attentional deficits and a generally severe disorganization of behavior. It can also involve other symptoms such as changes in energy levels, deficits in perception, an altered sleep-wake cycle, hallucinations, delusions, and psychosis.

Delirium may present itself in three distinct forms. These are referred to in the scientific literature as hyperactive, hypoactive, or mixed forms.[1] In its hyperactive form, it is manifested as severe confusion and disorientation, with a sudden onset and a fluctuating intensity.[2] In its hypoactive (i.e. underactive) form, it is manifested by an equally sudden withdrawal from interaction with the outside world accompanied by symptoms such as drowsiness and general inactivity.[3] Delirium may also occur in a mixed type in which one can fluctuate between both hyper and hypoactive periods.

Delirium is most commonly induced under the influence of heavy dosages of deliriant compounds, such as DPH, datura, and benzydamine. However, it can also occur as a result of an extremely wide range of health problems such as urinary tract infections, influenza, and alzheimer’s.[Controversial]

Psychoactive substances

Compounds within our psychoactive substance index which may cause this effect include:

See also

External links


  1. Delirium in elderly adults: diagnosis, prevention and treatment (ncbi) |
  2. Delerium ( |
  3. Hypoactive delirium (bmj) |