Bromo-DragonFLY

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Bromo-DragonFLY has been linked to an unusually large number of fatalities and hospitalizations.[1]

Due to its extremely high potency and unstudied effects, it is strongly discouraged to take this substance without taking the utmost harm reduction precautions, such as volumetric dosing, backup hospitalizations plans, and limiting intake to oral ingestion. Please see this section for more details.

Summary sheet: Bromo-DragonFLY
Bromo-DragonFLY
Bromo-DragonFLY.svg
Chemical Nomenclature
Common names Bromo-DragonFLY, DOB-DragonFLY, B-DFLY, Dragonfly
Substitutive name 8-bromo-4-(2-aminopropyl)benzodifuran
Systematic name (1-(8-bromobenzo[1,2-b;4,5-b']difuran-4-yl)-2-aminopropane
Class Membership
Psychoactive class Psychedelic
Chemical class Phenethylamine / Benzodifuran
Routes of Administration

WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section.



Oral
Dosage
Threshold Common Heavy
75 - 100 - 300 - 500 - 750 µg
Light Strong
Threshold 75 - 100 µg
Light 100 - 300 µg
Common 300 - 500 µg
Strong 500 - 750 µg
Heavy 750 µg +
Duration
Total 1 - 4 days
Onset 2 - 7 hours
Come up 3 - 6 hours
Peak 6 - 12 hours
Offset 3 - 8 hours
After effects 12 - 36 hours









DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy.

Bromo-DragonFLY (also known as DOB-DragonFLY or simply B-DFLY or Dragonfly) is a synthetic psychedelic substance of the substituted amphetamine and phenethylamine chemical classes. It produces an array of extremely dose-sensitive psychedelic effects when administered. It was first synthesized in 1998 by Matthew Parker from DOB-FLY.[citation needed]

Bromo-DragonFLY is extremely potent and produces unusually long effects which reportedly can last up to several days. It is considered to have one-third the potency of LSD by weight, making it remarkably potent relative to the vast majority of psychedelics.[citation needed]

Due to its high potency and unpredictable dose-response, many reports indicate that the effects of this substance may end up being overly difficult to use safely for those who are not already experienced with hallucinogens. Specifically, given that the dosage and duration of this substance have yet not been fully determined, users are advised to start at the lowest possible, intake only through the oral routes of administration, and never re-dose during any time throughout the experience.

Very little is known about the pharmacology, metabolism and toxicity about Bromo-DragonFLY in humans. It briefly gained popularity among research chemicals circa 2010 until several deaths occurred after the substance was accidentally mislabeled and sold as 2C-B-FLY, leading to its prohibition.[2]

Bromo-DragonFLY has never been documented as being sold on the street and has seemingly stopped production on research chemicals gray market. Due to its novelty and extremely short history of human usage, all information related to the use of this compound should be received with extreme caution. It is strongly recommended that one use the utmost harm reduction practices if choosing to take this substance.

Chemistry

Bromo-DragonFLY is a substituted phenethylamine, amphetamine and benzofuran, featuring a phenyl ring bound to an amino (NH2) group through an ethyl chain and contains a bromine atom attached to carbon R4. Bromo-DragonFLY is an atypical psychedelic phenethylamine which is closely analogous to DOB; it is the difuran analog to DOB, where it incorporates the methoxy groups bound to R2 and R5 of DOB into five member furan rings fused to the central benzene ring.

Bromo-DragonFLY belongs to a group of phenethylamine derivatives referred to as the DragonFLY compounds, named for their insect-like appearance of two “wing-like” furan rings fused on the opposite sides of the central benzene ring.

It is worth noting that the R-isomer of the molecule is considerably more active than the other and as such doses must be adjusted accordingly.

Pharmacology

Further information: Serotonergic psychedelic

The hallucinogenic effect of bromo-DragonFLY is mediated by its agonist activity at the 5-HT2A serotonin receptor. Bromo-DragonFLY also has a high binding affinity for the 5-HT2B and 5-HT2C serotonin receptors, and is most accurately described as a non-subtype selective 5-HT2 agonist, as it is actually twice as potent an agonist for 5-HT2C receptors as for 5-HT2A, as well as being less than 5x selective for 5-HT2A over 5-HT2B.[3][4]

However, the role of these interactions and how they result in the psychedelic experience continues to remain elusive.

Subjective effects

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This subjective effect breakdown is a stub.

As such, it may contain incomplete or wrong information and is still in progress.

You can help by expanding it.

Compared to LSD, this compound presents a significantly less pronounced body high, reduced visual effects and more in-depth hallucinations which are comparable to mescaline or 2C-B. Despite the visual and physical effects, it reportedly tends to maintain a level of sober thought structure. As the user usually retains acute cognitive sobriety, Bromo-DragonFLY can be considered to have diminished effects of confusion and potential delusions when compared to 4-AcO-DMT, psilocin, or LSD.

The effects listed below are based upon the subjective effects index and personal experiences of PsychonautWiki contributors. The listed effects should be taken with a grain of salt and will rarely (if ever) occur all at once, but heavier doses will increase the chances and are more likely to induce a full range of effects. Likewise, adverse effects become much more likely on higher doses and may include serious injury or death.

Physical effects
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Visual effects
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After effects
Aftereffects (3).svg

Experience reports

Anecdotal reports which describe the effects of this compound within our experience index include:

Additional experience reports can be found here:

Toxicity and harm potential

Bromo-DragonFLY can be considered extremely toxic at very high dosages with several deaths and numerous hospitalizations reported on overdoses.[5][6] It can also have extreme vasoconstrictive effects, which can result in severe tissue damage or even limb amputation. Due to its high potency, one can easily overdose if this substance is not measured correctly ("eyeballed") or mislabeled as another substance.

The toxicity and long-term health effects of recreational Bromo-DragonFLY do not seem to have been studied in any scientific context and the exact toxic dose is unknown. This is because Bromo-DragonFLY is a research chemical with very little history of human usage.

It is strongly recommended that one use harm reduction practices, such as volumetric dosing, when using this substance to ensure the accurate administration of the intended dose.

Notable deaths

On May 7, 2011, in the United States, two young adults died and several others were hospitalized after overdosing on Bromo-DragonFLY, which they believed was 2C-E.[7]

Tolerance and addiction potential

Bromo-DragonFLY is not habit-forming and the desire to use it can actually decrease with use. It is most often self-regulating.

Tolerance to the effects of Bromo-DragonFLY are built almost immediately after ingestion. After that, it takes about 6 days for the tolerance to be reduced to half and 14 days to be back at baseline (in the absence of further consumption). Bromo-DragonFLY presents cross-tolerance with all psychedelics, meaning that after the consumption of Bromo-DragonFLY all psychedelics will have a reduced effect.

Dangerous interactions

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This dangerous interactions section is a stub.

As such, it may contain incomplete or invalid information. You can help by expanding upon or correcting it.

Although many psychoactive substances are safe on their own, they can become dangerous and even life-threatening when combined with other substances. The list below contains some common potentially dangerous combinations, but may not include all of them. Certain combinations may be safe in low doses of each but still increase the potential risk of death. Independent research should always be done to ensure that a combination of two or more substances is safe before consumption.

Legal status

  • Australia: Bromo-DragonFLY is nationally a Schedule 9 substance, making it illegal to possess, produce and sell.[citation needed]
  • Canada: Bromo-DragonFLY was listed as a Schedule III Substance as of October 12, 2016, along several other research chemicals.[citation needed]
  • Denmark: Possession, production and sale is illegal.[citation needed]
  • Finland: Possession, production and sale is illegal.[citation needed]
  • Norway: Bromo-DragonFLY is considered a narcotic in Norway.[citation needed]
  • Romania: Possession, production and sale is illegal.[citation needed]
  • Sweden: Bromo-DragonFLY is listed as a Schedule IV substance, making it illegal to possess, produce and sell.[citation needed]
  • United Kingdom - It is illegal to produce, supply, or import this substance under the Psychoactive Substance Act, which came into effect on May 26th, 2016.[9]
  • United States: Bromo-DragonFLY is listed as a Schedule I substance in Oklahoma.[citation needed]

See also

External links

References

  1. Bromo-Dragonfly Fatalities / Deaths by Erowid | https://www.erowid.org/chemicals/bromo_dragonfly/bromo_dragonfly_death.shtml
  2. https://erowid.org/chemicals/bromo_dragonfly/bromo_dragonfly_death.shtml
  3. A novel (benzodifuranyl)aminoalkane with extremely potent activity at the 5-HT2A receptor | https://www.ncbi.nlm.nih.gov/pubmed/9857084
  4. Designer drugs on the internet: a phenomenon out-of-control? the emergence of hallucinogenic drug Bromo-Dragonfly. | https://www.ncbi.nlm.nih.gov/pubmed/21592070?dopt=Abstract
  5. "| Danish man died after trip on Chinese drug". Jp.dk. Retrieved 2010-02-08. 
  6. "Narkodød skyldtes ikke GHB". RB.no. Retrieved 2018-05-16. 
  7. [1]
  8. Talaie, H., Panahandeh, R., Fayaznouri, M. R., Asadi, Z., & Abdollahi, M. (2009). Dose-independent occurrence of seizure with tramadol. Journal of medical toxicology, 5(2), 63-67. https://doi.org/10.1007/BF03161089
  9. Psychoactive Substances Act 2016 (Legislation.gov.uk) | http://www.legislation.gov.uk/ukpga/2016/2/contents/enacted