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Confusion can be described as a state of being bewildered or unclear in one’s mind about something.[1][2] Within the context of substance use, it is commonly experienced as a persistent inability to grasp or comprehend concepts and situations which would otherwise be perfectly understandable during sobriety. The intensity of this effect seems to to be further increased when a person is unfamiliar with the substance they are on.

Confusion is often accompanied by other coinciding effects such as delirium, delusions, and short term memory suppression in a manner which further increases the person's lack of comprehension. It is most commonly induced under the influence of heavy dosages of hallucinogenic compounds, such as psychedelics,[3] dissociatives,[4] cannabinoids, and deliriants.[5] However, it can also occur to a lesser extent under the influence of heavy dosages of benzodiazepines and antipsychotics.

Psychoactive substances

Compounds within our psychoactive substance index which may cause this effect include:

See also

External links


  1. Confusion (Psychology Dictionary) |
  2. Confusion definition (Oxford dictionary) |
  3. Krebs, T. S., & Johansen, P. Ø. (2013). Psychedelics and mental health: a population study. PloS one, 8(8), e63972.
  4. Mozayani, A. (2003). Phencyclidine-Effects on Human Performance and Behavior. Forensic science review, 15(1), 61-74.
  5. Datura effects (Erowid) |