Confusion can be described as a state of being bewildered or unclear in one’s mind about something. Within the context of substance use, it is commonly experienced as a persistent inability to grasp or comprehend concepts and situations which would otherwise be perfectly understandable during sobriety. The intensity of this effect seems to to be further increased when a person is unfamiliar with the substance they are on.
Confusion will often synergize with other coinciding effects such as delirium, delusions, and short term memory suppression in a manner which further increases one's lack of comprehension. It is most commonly induced under the influence of heavy dosages of hallucinogenic compounds such as psychedelics, dissociatives, deliriants, and salvia divinorum. However, it may also occur more inconsistently with heavy dosages of benzodiazepines and antipsychotics.
Compounds within our psychoactive substance index which may cause this effect include: