Mouth numbing

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Mouth numbing is a physical side effect of administering certain drugs sublingually (under the tongue) or buccally. This effect can be described as an obvious feeling of general numbness of the tongue and mouth which can stay for up to an hour after the drug has been administered.

The NBOMe series (25C-NBOMe, 25B-NBOMe, and 25I-NBOMe) cause this effect consistently and it is accompanied by a strong, unpleasant, metallic chemical taste immediately after sublingual absorption. As LSD does not cause numbing or a strong chemical taste, this is the key difference when it comes to determining whether your blotter paper contains LSD or another psychoactive chemical such as one of the NBOMe series.

The stimulant cocaine also causes numbing of the tongue, gums, and mouth when administered sublingually. Many people test the purity of their cocaine by rubbing it in their mouth. This, however, is not a guarantee of the drug's quality as it is common for cocaine to be cut with various numbing agents and local anesthetics (such as procaine, AKA novocaine, lidocaine, or benzocaine) which mimic or add to cocaine's numbing effect.

Psychoactive substances

Compounds within our psychoactive substance index which may cause this effect include:

Experience reports

Anecdotal reports which describe this effect within our experience index include:

See also