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Death may result when GABAergic substances are combined with other depressants such as opiates, benzodiazepines, barbiturates, gabapentinoids, thienodiazepines or alcohol.[1]

It is strongly discouraged to combine these substances, particularly in common to heavy doses.


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It may contain incorrect information, particularly with respect to dosage, duration, subjective effects, toxicity and other risks.

Summary sheet: Zaleplon
Chemical Nomenclature
Common names Sonata, Starnoc, Andante
Substitutive name Zaleplon
Systematic name N-[3-(3-cyanopyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-N-ethylacetamide
Class Membership
Psychoactive class Depressant / Hypnotic / Hallucinogen
Chemical class Pyrazolopyrimidine
Routes of Administration

WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section.

Threshold 5 - 10 mg
Light 10 - 30 mg
Common 30 - 60 mg
Strong 60 - 100 mg
Heavy 100 mg +
Total 90 - 120 minutes
Onset 5 - 15 minutes
Peak 30 - 60 minutes
Offset 10 - 20 minutes
After effects 2 - 4 hours

DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy.

Zaleplon (trade name Sonata) is a non-benzodiazepine hypnotic drug. It is of the hypnotic and depressant psychoactive classes and is chemically a pyrazolopyrimidine. When taken for recreational purposes, at doses far higher then the prescribed dose, it is capable of producing powerful and bizarre atypical hallucinogenic, hypnotic, deliriant and even psychedelic effects.

Zaleplon is a member of a family known as "Z-drugs." Other Z-drugs include Zolpidem (Ambien) and zopiclone. These drugs were initially thought to be less addictive and/or habit-forming than benzodiazepines. However, this evaluation has shifted in the last few years as cases of addiction and habituation have accumulated.[citation needed]

Zaleplon is recommended to be taken on a short-term basis only. Daily or continuous use of the drug is not usually advised.

History and culture

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This chemistry section is incomplete.

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Zaleplon is a GABABZ receptor agonist as well as a GABAA agonist. [2]

Subjective effects

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Disclaimer: The effects listed below are cited from the subjective effect index, which is based on anecdotal reports and the personal experiences of PsychonautWiki contributors. As a result, they should be treated with a healthy degree of skepticism. It is worth noting that these effects will rarely (if ever) occur all at once, although higher doses will increase the chances of inducing a full range of effects. Likewise, adverse effects become much more likely on higher doses and may include serious injury or death.

Physical effects

Disconnective effects

Visual effects

Cognitive effects

Auditory effects

Experience reports

There are currently no anecdotal reports which describe the effects of this compound within our experience index. Additional experience reports can be found here:

Toxicity and harm potential


This toxicity and harm potential section is a stub.

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We also recommend that you conduct independent research and use harm reduction practices when using this substance.

As with other Z-drugs, zaleplon use may result in bizarre and dangerous behavior.

It is strongly recommended that one use harm reduction practices when using this substance.

Lethal dosage

Tolerance and addiction potential

Zaleplon has similar withdrawal symptoms to other non-benzodiazepines.

Dangerous interactions


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Although many psychoactive substances are reasonably safe to use on their own, they can quickly become dangerous or even life-threatening when taken with other substances. The following lists some known dangerous combinations, but cannot be guaranteed to include all of them. Independent research should always be conducted to ensure that a combination of two or more substances is safe to consume. Some interactions listed have been sourced from TripSit.

  • Stimulants - It can be dangerous to combine depressants with stimulants due to the risk of accidental excessive intoxication. Stimulants mask the sedative effect of depressants, which is the main factor most people use to gauge their level of intoxication. Once the stimulant effects wear off, the effects of the depressant will significantly increase, leading to intensified disinhibition, motor control loss, and dangerous black-out states. This combination can also potentially result in severe dehydration if one's fluid intake is not closely monitored. If choosing to combine these substances, one should strictly limit themselves to a pre-set schedule of dosing only a certain amount per hour until a maximum threshold has been reached.

Legal status


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As such, it may contain incomplete or wrong information. You can help by expanding it.

  • United States - Zaleplon is Schedule IV under the Controlled Substance Act (CSA), meaning it is judged to have "some potential for abuse."" Possession without a prescription is illegal.
  • Canada - Zaleplon is not scheduled in Canada. However, it may be illegal to possess without a valid prescription. [citation needed]
  • Russia: Zaleplon is available through a prescription.[citation needed]

See also

External links