Orgasm depression
Orgasm depression (formally known as anorgasmia) can be described as a difficulty or complete inability to achieve orgasm despite adequate sexual stimulation.[1] It can also include suppressed feelings during an orgasm or sexual pleasure.
This effect commonly occurs on opioids, gabapentinoids and dissociatives which have been reported to decrease one's ability to feel sexual pleasure, which may be attributed to their tactile suppressing effects or through some other biological mechanism.[citation needed] It is also a well-known side effect of selective serotonin reuptake inhibitors (SSRIs).[2] It may also be a result of the effect known as difficulty urinating which can occur on certain stimulants and entactogens. This effect has been reported to occur alongside a decrease in the strength of one's kegel muscles, which may account for the inability to achieve ejaculation and orgasm within males.
Psychoactive substances
Compounds within our psychoactive substance index which may cause this effect include:
- 2-Fluorodeschloroketamine
- 3-Cl-PCP
- 3-HO-PCP
- 3-MMC
- 4-FA
- 4-FMA
- 4F-EPH
- Acetylfentanyl
- Baclofen
- Buprenorphine
- Codeine
- Deschloroketamine
- Desomorphine
- Dextromethorphan
- Dextropropoxyphene
- Dihydrocodeine
- Diphenidine
- Ephenidine
- Ethylmorphine
- Fentanyl
- GHB
- HXE
- Heroin
- Hydrocodone
- Hydromorphone
- Ketamine
- Kratom
- LSA
- MDMA
- MXiPr
- Memantine
- Methadone
- Methoxetamine
- Methoxphenidine
- Morphine
- O-Desmethyltramadol
- O-PCE
- Oxycodone
- Oxymorphone
- Pethidine
- Phenibut
- Pregabalin
- Prochlorperazine
- Quetiapine
- Selective serotonin reuptake inhibitor
- Tapentadol
- Tramadol
Experience reports
Anecdotal reports which describe this effect with our experience index include:
See also
External links
References
- ↑ Brindley, G. S., Gillan, P. (April 1982). "Men and Women Who Do Not Have Orgasms". British Journal of Psychiatry. 140 (4): 351–356. doi:10.1192/bjp.140.4.351. ISSN 0007-1250.
- ↑ Ashton, A. K., Hamer, R., Rosen, R. C. (1 September 1997). "Serotonin reuptake inhibitor-induced sexual dysfunction and its treatment: A large-scale retrospective study of 596 psychiatric outpatients". Journal of Sex & Marital Therapy. 23 (3): 165–175. doi:10.1080/00926239708403922. ISSN 0092-623X.