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|Summary sheet: Troparil|
|Common names||Troparil, WIN 35,065-2, β-CPT|
|Systematic name||Methyl (1R,2S,3S,5S)-3-(phenyl)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate|
|Routes of Administration|
Being an only recently introduced research chemical, extremely little is known about the pharmacology, metabolism, and toxicity of troparil in humans. It is highly advised to use harm reduction practices if choosing to use this substance.
- 1 History and culture
- 2 Chemistry
- 3 Pharmacology
- 4 Subjective effects
- 5 Toxicity and harm potential
- 6 Legal status
- 7 See also
- 8 External links
- 9 Literature
- 10 References
History and culture
This History and culture section is a stub.
As a result, it may contain incomplete or wrong information. You can help by expanding it.
Troparil primarily acts as a dopamine reuptake inhibitor (DRI). While this effect is a few times more potent as with cocaine, the effect of troparil on serotonin reuptake inhibition is slightly less pronounced.
|Cocaine||89 ± 4.8||3298 ± 293||1045 ± 89|
|Dichloropane||0.79 ± 0.09||17.96 ± 0.85||3.13 ± 0.36|
|Troparil||23 ± 5||920 ± 73||1962 ± 61|
Effects of troparil are thought to be similar to cocaine, albeit longer lasting.
The effects listed below are based on the subjective effect index, which is based on anecdotal reports and the personal experiences of PsychonautWiki contributors. As a result, they should be treated with a healthy amount of skepticism. It is worth noting that these effects will rarely (if ever) occur all at once but heavier doses will increase the chances of inducing a full range of effects. Likewise, adverse effects become much more likely on higher doses and may include serious injury or death.
- Increased heart rate
- Abnormal heartbeat - This substance consistently raises one's heart rate to abnormally high levels which can be potentially dangerous with prolonged or extremely high dosages.
- Appetite suppression
- Bodily control enhancement
- Increased bodily temperature
- Increased blood pressure
- Increased perspiration
- Pain relief
- Physical euphoria
- Teeth grinding
- Temporary erectile dysfunction
- The effects which occur during the offset of a stimulant experience generally feel negative and uncomfortable in comparison to the effects which occurred during its peak. This is often referred to as a "comedown" and occurs because of neurotransmitter depletion.
Toxicity and harm potential
This toxicity and harm potential section is a stub.
As such, it may contain incomplete or even dangerously wrong information. You can help by expanding or correcting it.
The toxicity and long-term health effects of recreational troparil use has not been studied in any scientific context and the exact toxic dosage is unknown. This is because troparil has very little history of human usage.
There is no research demonstrating so, but due to the lack of an ester linkage, troparil might possibly be slightly less cardiotoxic than cocaine. Nevertheless, it still poses a risk to the cardiovascular system and should not be used with a pre-existing heart condition.
It is strongly recommended that one use harm reduction practices when using this substance.
Tolerance and addiction potential
This dangerous interactions section is a stub.
As such, it may contain incomplete or invalid information. You can help by expanding upon or correcting it.
Although many psychoactive substances are reasonably safe to use on their own, they can quickly become dangerous or even life-threatening when taken with other substances. The following lists some known dangerous combinations, but cannot be guaranteed to include all of them. Independent research should always be conducted to ensure that a combination of two or more substances is safe to consume. Some interactions listed have been sourced from TripSit.
This legality section is a stub.
As such, it may contain incomplete or wrong information. You can help by expanding it.
- Synthesis and pharmacology of site specific cocaine abuse treatment agents: 8-substituted isotropane (3-azabicyclo[3.2.1]octane) dopamine uptake inhibitors. | http://pubs.acs.org/doi/abs/10.1021/jm020410t
- Cocaine and 3.beta.-(4'-Substituted phenyl)tropane-2.beta.-carboxylic Acid Ester and Amide Analogs. New High-Affinity and Selective Compounds for the Dopamine Transporter | http://pubs.acs.org/doi/abs/10.1021/jm00002a020
- Synthesis and Monoamine Transporter Binding Properties of 3β-(3‘,4‘-Disubstituted phenyl)tropane-2β-carboxylic Acid Methyl Esters | http://pubs.acs.org/doi/abs/10.1021/jm040185a