Talk:Bromazolam
For chemistry section: Although the name might suggest that Bromazolam is the triazolobenzodiazepine derivate of bromazepam, that would actually be pyrazolam. As such, bromazolam could be considered to be named bromodeschloroalprazolam instead.
PsychonautWiki desperately needs an informative, accurate Bromazolam article
I would do it but this is my first time editing a Wiki. I will help in any way possible Battleboner (talk) 19:30, 3 April 2023 (UTC)
I have researched Bromazolam for a few years. I made this account to contribute information specifically for this compound. In my years of research, I have found this information to be accurate:
Dosing range: Threshold: .25mg Light: .5mg-1mg Moderate: 1mg-2mg Strong: 2mg-4mg
Onset: 15min-1hr
Duration of effects: 5-6hrs
This is a strong benzo. It is my opinion that it is as/more potent than alprazolam, however at higher doses it exhibits hypnotic effects. AltusNoidus (talk) 00:42, 25 July 2024 (UTC)
Addendum: I should also say that strong doses are really not recommended. This compound does not perform well with increased dosage amount.
It causes delusions of sobriety and confusion, it acts as a "sedative-hypnotic" almost like Zolpidem, except at a strong dose you also have ataxia, complete disinhibition, and in some cases dissociation. It is not a good compound for recreational use, and I wouldn't bother if you're looking to use it for that. AltusNoidus (talk) 00:26, 28 July 2024 (UTC)
Bromazolam information in the article and Discussion section is in some cases wildly underplayed. Article should be quarantined while we figure out wtf is going on here. Bromazolam is a powerful alprazolam analogue almost mg per mg as powerful.
Bromazolam information in the article and Discussion section is in some cases wildly underplayed. Article should be quarantined while we figure out wtf is going on here. Bromazolam is a powerful alprazolam analogue almost mg per mg as powerful.
Bromazolam Dosage guidlines and duration of effects from fairly recent WHO Critical Review report
Page 8 of their reports on ROA's and dosage seemed most particularly helpful.
Light dosage range is reported to be: (05mg-1mg) Common dosage range is reported to be: (1mg-2mg) Strong/heavy dosage range is reported to be:(2mg-4mg)
"Onset of effects after oral use is estimated to be 15–45 min, and the duration of action is 5–8 h." - WHO Critical Review findings
I have used this compound in research for years, and I can confirm that the dosing range is in fact accurate, as well as the duration of effects. AltusNoidus (talk) 00:31, 25 July 2024 (UTC)
This Could use a page By Now
This substance is fairly popular now, because of law reasons.
Its effects seem almost identical to Alprazolam, so does the dosage and the predicted binding seems to match the experienced effects (from what i can understand of the reports, and talking to some people on harm reduction communities)
https://tripsit.me/factsheets/bromazolam https://www.drugsinfo.nl/overige-middelen/bromazolam https://cdn.who.int/media/docs/default-source/46th-ecdd/bromazolam_46th-ecdd-critical-review_public-version.pdf?sfvrsn=4f1bccfa_1
Like Pyrazolam/Alprazolam there are some early concerning reports regarding, re-reenforcing and withdrawal effects https://drugsforum.nl/threads/bromazolam.67875/post-1692592 This could be entirely because of the pharmakinetic effects (fast absorption rate and short duration)
There is a single piece of animal research
The abuse potential of bromazolam at 0.1–3 mg/kg was evaluated in male rats trained to discriminate the benzodiazepine midazolam in a standard two-lever drug discrimination study (29). Like midazolam and diazepam, bromazolam resulted in full dose-dependent substitution for the 0.3 mg/kg training dose of midazolam, with an ED50 (± 95% confidence interval [CI]) of 0.54 (0.26 ; 1.12) mg/kg. In comparison, the ED50 (± 95% CI) was 0.09 (0.06; 0.14) mg/kg for midazolam and 0.66 (0.40 ; 1.12) mg/kg for diazepam. At the dose range tested, bromazolam did not affect response rates. The midazolam-like effects of bromazolam at 3 mg/kg were significantly attenuated by pre-administration of the benzodiazepine receptor antagonist flumazenil at 1 mg/kg. Morphine, tested as a negative control, did not produce a response on the midazolam-associated lever at doses that suppressed the overall response rate.
Single experience report
https://www.erowid.org/experiences/exp.php?ID=115168
Other Sources
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7569319/ https://en.wikipedia.org/wiki/Bromazolam
Sadly no human research on these substances exist, but it seems to me that the research about predicting the binding efficient of certain benzo analogs was simply too successful to require anything else for recreational use, this should just be a simple Halogenic substitution of Aprazolam and it seems to behave exactly as expected.
Also don’t understand why Bromazolam doesn’t have its own page, since it’s a very popular RC benzo.
It’s my pet rats favorite. My rat told me, it’s very close to Alprazolam in Dosage & also high.
Biggest difference is, it is a ”clearer“ high. It doesn’t fog up your brain, like Alprazolam does. Kenz0r (talk) 21:28, 12 March 2024 (UTC)
needs a page badly
at least some basic information. got a good bit of experience on this and most posts on r/researchchemicals seem to agree this is the closest rc to alprazolam. also compared to most rc benzos this seems to be one of the best.
i don‘t take benzos reguarly but this one seems really promising. no long half life. really cheap and easy to dose volumetrically. fairly potent in moderate consumption. really good tripkiller.
just like 2-fdck is really similar to ket, broma seems really similar to alpras.
used this like 10 times so could write some reports about roa, length, strength at least. also saved my ass on an accidental 25e-nboh overdose. Saferusenshizz (talk) 16:28, 4 June 2024 (UTC)
I agree with reports of being 1:1 with Alprazolam as I've used both regularly in the past few months. Bromazolam was on the list of now banned substances to manufacture in China, but the sheer amount of product already produced is staggering so it will be a long while before we see supply drain. In my area of the USA, it is being sold in 4mg U94 Xanax and 4mg V2909 Xanax white pressed bars. Insanely cheap, bulk 4mg bars going for under $0.5 USD / each has me most concerned for user safety and addiction potential. TOP (talk) 05:25, 21 July 2024 (UTC)