Talk:Semax

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Summary sheet: Semax
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Semax
Semax.svg
Chemical Nomenclature
Common names Semax
Substitutive name L-Methionyl-L-α-glutamylhistidyl-L-phenylalanyl-L-prolylglycyl-L-proline
Systematic name (2S)-1-[2-{[(2S)-1-[(2S)-2-{[2-{[(2S)-2-{[(2S)-2-amino-4-methylsulfanylbutanoyl]amino}-4-carboxybutanoyl]amino}-3-(1H-imidazol-5-yl)propanoyl]amino}-3-phenylpropanoyl]pyrrolidine-2-carbonyl]amino}acetyl]pyrrolidine-2-carboxylic acid
Class Membership
Psychoactive class Stimulant / Nootropic
Chemical class Peptide
Routes of Administration

WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section.






Insufflated
Dosage
Bioavailability 60 - 70%[1]
Threshold 50 µg
Light 50 - 100 µg
Common 100 - 500 µg
Strong 500 - 1200 µg
Heavy 1200 µg +
Duration
Total 8 - 20 hours
Onset 1 - 30 minutes
Peak 4 - 8 hours
Offset 2 - 12 hours
After effects 12 - 24 hours



Subcutaneous
Dosage
Bioavailability ~99%
Duration



DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy.

Interactions

Semax (sometimes mistakenly called C-Max) is an obscure member of the psychoactive class: peptides

Semax is a Russian nootropic drug that is used as nasal drops or as subcutaneous injections within the nootropics community to improve cognitive functions and treat various medical conditions (within Russia). By its structure, Semax is a fragment of endogenous neuropeptide ACTH (Adrenocorticotropic hormone). The drug was shown to increase BDNF (Brain Derived Neurotropic Factor) that is responsible for the growth and differentiation of new neurons and synapses.


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History and culture

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Chemistry

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Pharmacology

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Subjective effects

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Disclaimer: The effects listed below cite the Subjective Effect Index (SEI), an open research literature based on anecdotal user reports and the personal analyses of PsychonautWiki contributors. As a result, they should be viewed with a healthy degree of skepticism.

It is also worth noting that these effects will not necessarily occur in a predictable or reliable manner, although higher doses are more liable to induce the full spectrum of effects. Likewise, adverse effects become increasingly likely with higher doses and may include addiction, severe injury, or death ☠.

Physical effects
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Visual effects
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Cognitive effects
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Auditory effects
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Multi-sensory effects
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Transpersonal effects
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Experience reports

There are currently 0 experience reports which describe the effects of this substance in our experience index.

Additional experience reports can be found here:

Toxicity and harm potential

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Note: Always conduct independent research and use harm reduction practices if using this substance.

It is strongly recommended that one use harm reduction practices when using this substance.

Lethal dosage

Tolerance and addiction potential

Dangerous interactions

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Warning: Many psychoactive substances that are reasonably safe to use on their own can suddenly become dangerous or even life-threatening when combined with certain other substances. The following lists some known dangerous interactions (although it is not guaranteed to include all of them).

Always conduct independent research (e.g. Google, DuckDuckGo, PubMed) to ensure that a combination of two or more substances is safe to consume. Some of the listed interactions have been sourced from TripSit.

Legal status

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See also

External links

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Literature

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References