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Summary sheet: MPT
Chemical Nomenclature
Common names MPT, Methylpropyltryptamine
Substitutive name N-Methyl-N-propyltryptamine
Systematic name N,N-diethyl-2-(1H-indol-3-yl)ethanamine
Class Membership
Psychoactive class Psychedelic
Chemical class Tryptamine
Routes of Administration

WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section.

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DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy.


N-Methyl-N-propyltryptamine (abbreviated MPT; also known as Methylpropyltryptamine) is a synthetic psychedelic of the tryptamine class that has reported to display powerful hallucinogenic and sometimes entactogenic effects. It is structurally analogous to N,N-dimethyltryptamine (DMT) and various base psychedelic tryptamines by which one can have a "breakthrough" experience such as MET, EPT, and DPT.

While little is known aboout the pharmacology of this substance, early reports indicate it shares that vaporizing or freebasing the compounds shares most of the core components of the DMT experience, just with its own stylistic pharmacodynamic and kinetic variations.[citation needed]

MPT is extremely uncommon and has little history of human usage. It has never been documented as being sold on the street and is instead primarily acquired through the use of research chemical vendors and outfits who specialize in the sale of exotic psychoactive chemicals.[citation needed]


Generic structure of a tryptamine molecule

This chemistry section is incomplete.

You can help by adding to it.


Further information: Serotonergic psychedelic

Due to the lack of research regarding the substance, all discussion regarding the pharmacology of it is purely based on its structure and subjective effect similarities to other tryptamine psychedelics such as psilocin and DMT. With this in mind, MPT is thought to act as an 5-HT2A partial agonist.

However, the role of these interactions and how they result in the psychedelic experience continues to remain elusive.

Subjective effects

This subjective effects section is a stub.

As such, it is still in progress and may contain incomplete or wrong information.

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The effects listed below are based upon the subjective effects index and personal experiences of PsychonautWiki contributors. These effects should be taken with a grain of salt and will rarely (if ever) occur all at once, but heavier doses will increase the chances of inducing a full range of effects. Likewise, adverse effects become much more likely on higher doses and may include serious injury or death.

Experience reports

There are currently no anecdotal reports which describe the effects of this compound within our experience index. Additional experience reports can be found here:

Toxicity and harm potential

The toxicity and long-term health effects of recreational MPT use do not appear to have been studied in any scientific context and the exact toxic dose is unknown. This is because MPT is a research chemical with very little history of human use. Anecdotal evidence from people within the psychonaut community who have tried MPT suggests that there are no negative health effects attributed to simply trying the drug by itself at low to moderate doses and using it very sparingly (but nothing can be completely guaranteed). Independent research should always be done to ensure that a combination of two or more substances is safe before consumption.

It is strongly recommended that one uses harm reduction practices when using this drug.

Tolerance and addiction potential

MPT is not habit-forming and the desire to use it can actually decrease with use. It is most often self-regulating.

Tolerance to the effects of MPT is built almost immediately after ingestion. After that, it takes about 3 days for the tolerance to be reduced to half and 7 days to be back at baseline (in the absence of further consumption). MPT presents cross-tolerance with all psychedelics, meaning that after the consumption of MPT all psychedelics will have a reduced effect.

Dangerous interactions

Although many drugs are safe on their own, they can become dangerous and even life-threatening when combined with other substances. The list below contains some common potentially dangerous combinations, but may not include all of them. Certain combinations may be harmless in low doses of each but still increase the potential risk of death. Independent research should always be done to ensure that a combination of two or more substances is safe before consumption.

  • Tramadol - Tramadol lowers seizure threshold[1] and psychedelics may cause occasional seizures.
  • Stimulants - Stimulants may provoke anxiety or thought loops.

Legal issues


This legality section is a stub.

As such, it may contain incomplete or wrong information. You can help by expanding it.

  • Germany: MPT is controlled under the NpSG as of July 18, 2019. [2] [3] Production and import for placing on the market and trade is punishable. Possession, although illegal, is not penalized if not intended for sale.[4]
  • United Kingdom - MPT is a Class A drug in the United Kingdom as a result of the tryptamine catch-all clause.[5]
  • United States - MPT is unscheduled in the United States. It may be considered an analogue of DET, a Schedule I drug under the Controlled Substances Act. As such, the sale for human consumption or the use for illicit non-medical or industrial intents and purposes could be prosecuted as crimes under the Federal Analogue Act.[citation needed]
  • New Zealand: MPT is an analogue of DMT, so is a Class C controlled drug in New Zealand.[6]

See also

External links