|Summary sheet: EPT|
|Routes of Administration|
N-Ethyl-N-propyltryptamine (also known as EPT) is an obscure novel psychedelic substance of the tryptamine class. EPT is chemically related to DMT and belongs to a series of psychedelic compounds known as unsubstituted tryptamines.
The original synthesis date of EPT is unknown. It first appeared for sale on the online research chemical market in 2016. Unlike most research chemicals, EPT has no documentation in the scientific literature. It appears to be an entirely novel product of clandestine drug design.
Initial reports describe the effects of EPT as mild and indistinct compared to structurally similar base tryptamines such as DMT, DET and DPT, all of which are highly powerful psychedelics. Of these, it is reported to be most similar to DPT, albeit less potent and with a less immersive headspace.
- 1 Chemistry
- 2 Pharmacology
- 3 Subjective effects
- 4 Toxicity and harm potential
- 5 Legal status
- 6 See also
- 7 External links
- 8 References
EPT, or N-ethyl-N-propyltryptamine, is a synthetic indole molecule of the tryptamine chemical class. Tryptamines share a core structure comprised of a bicyclic indole heterocycle attached at R3 to an amino group via an ethyl side chain. EPT features one propyl and one ethyl groups bound to the terminal amine RN of its tryptamine backbone.
Like with most psychedelic tryptamines, EPT is thought to act principally as a 5-HT2A partial agonist. The psychedelic effects are believed to come from EPT's binding efficacy at the 5-HT2A receptors.
However, the role of these interactions and how they result in the psychedelic experience remain the subject of ongoing scientific investigation.
|This subjective effects section is a stub.|
As such, it is still in progress and may contain incomplete or wrong information.
You can help by expanding or correcting it.
Disclaimer: The effects listed below are taken from the subjective effect index, which is based on anecdotal reports and the personal experiences of PsychonautWiki contributors. As a result, they should be treated with a healthy degree of skepticism. It is worth noting that these effects will rarely (if ever) occur all at once, although higher doses will increase the chances of inducing a full range of effects. Likewise, adverse effects become much more likely on higher doses and may include serious injury or death. The effects of EPT have not been researched as well as many other tryptamines. The following effects are drawn from a relatively limited sample size.
Anecdotal reports which describe the effects of this compound within our experience index include:
Additional experience reports can be found here:
Toxicity and harm potential
The toxicity and long-term health effects of recreational EPT use have not been studied in any scientific context and the exact toxic dose is unknown. This is because EPT is a research chemical with a very limited history of human usage.
Anecdotal evidence suggests that there are no negative health effects attributed to simply trying EPT by itself at low to moderate doses and using it very sparingly (but nothing can be completely guaranteed). Independent research should always be done to ensure that a combination of two or more substances is safe before consumption.
It is strongly recommended that one use harm reduction practices when using this substance.
Dependence and abuse potential
Unlike DMT, tolerance to the effects of EPT appear to form almost immediately after ingestion. After that, it takes about 3 days for the tolerance to be reduced to half and 7 days to be back at baseline (in the absence of further consumption). EPT produces cross-tolerance with all psychedelics, meaning that after the consumption of EPT all psychedelics will have a reduced effect.
This legality section is a stub.
As such, it may contain incomplete or wrong information. You can help by expanding it.
Due to its relative obscurity, the possession and sale of EPT is unscheduled in most countries.
- Germany: EPT is controlled under the NpSG as of July 18, 2019.   Production and import for placing on the market and trade is punishable. Possession, although illegal, is not penalized if not intended for sale.
- United Kingdom: EPT is a Class A drug in the United Kingdom as a result of the tryptamine catch-all clause.
- United States: EPT is unscheduled in the United States. It may be considered an analogue of DMT, which is a Schedule I drug under the Controlled Substances Act. As such, the sale for human consumption or the use for illicit non-medical or industrial intents and purposes could be prosecuted as crimes under the Federal Analogue Act.
- Misuse of Drugs Act 1971 (Legislation.gov.uk) |http://www.legislation.gov.uk/ukpga/1971/38/schedule/2/part/I#reference-M_F_c7632653-ddad-4420-f307-e3da1e36d30e