Ketamine/Summary

Main article: Ketamine

Psychoactive class: Dissociatives

Chemical class: Arylcyclohexylamines

Oral

• Thresh				Common				Heavy
  50	-	50	-	100	-	300	-	450	mg
  		Light				Strong

• • Onset: 10 - 30 minutes
  • Come up: 5 - 20 minutes
  • Peak: 45 - 90 minutes
  • Offset: 3 - 6 hours
  • Afterglow: 4 - 8 hours

Insufflated

• Thresh				Common				Heavy
  5	-	10	-	30	-	75	-	150	mg
  		Light				Strong

• • Total: 1 - 2 hours
  • Onset: 1 - 3 minutes
  • Come up: 5 - 15 minutes
  • Peak: 15 - 45 minutes
  • Offset: 30 - 60 minutes
  • Afterglow: 2 - 12 hours

Harm potential

• • Moderate to high abuse potential and produces psychological dependence with chronic use

Tolerance

• • Full tolerance is reached develops with prolonged and repeated use
  • Decreases to half after 3 - 7 days
  • Returns to baseline after 1 - 2 weeks
  • Cross-tolerance with all dissociatives

Physical effects

• • Perception of bodily lightness
  • Spatial disorientation
• • Pain relief
  • Sedation
• • Dehydration
  • Difficulty urinating
  • Dizziness
  • Increased blood pressure
  • Increased salivation
  • Nausea
  • Optical sliding

Visual effects

• • Auditory distortion
  • Environmental cubism
  • Environmental orbism
  • Perspective distortion
  • Scenery slicing
  • Time distortion
• • Pattern recognition suppression
  • Visual acuity suppression
  • Visual processing deceleration
• • Visual disconnection
• • Geometry
• • Autonomous entity
  • External hallucination
  • Internal hallucination
  • Perspective hallucination
  • Settings, sceneries, and landscapes

Cognitive effects

• • Cognitive euphoria
  • Compulsive redosing
  • Conceptual thinking
  • Time distortion
• • Increased music appreciation
• • Addiction suppression
  • Anxiety suppression
  • Disinhibition
  • Focus suppression
  • Memory suppression
  • Personal bias suppression
  • Thought deceleration

Auditory effects

• • Auditory acuity suppression
  • Auditory distortion
  • Auditory hallucination

Multi-sensory

• • Machinescapes
  • Psychosis
  • Scenarios and plots
  • Synaesthesia

See also

• Responsible use
• Summary index
• Subjective effect index
• Psychoactive substance index