Baclofen/Summary

Main article: Baclofen

Psychoactive class: Depressant

Chemical class: Gabapentinoids

Oral

• Thresh				Common				Heavy
  5	-	10	-	20	-	50	-	100	mg
  		Light				Strong

• • Total: 8 - 14 hours
  • Onset: 30 - 75 minutes
  • Peak: 60 - 90 minutes
  • Afterglow: 6 - 12 hours

Harm potential

• • Moderately physically and psychologically addictive
  • Low toxicity, potentially lethal when mixed with depressants like alcohol, benzodiazepines or opioids

Tolerance

• • Full tolerance is reached within a couple of days of continuous use
  • Returns to baseline after 7 - 14 days
  • Cross-tolerance with all GABAgenic depressants

Physical effects

• • Stimulation
• • Pain relief
  • Respiratory depression
  • Sedation
• • Decreased blood pressure
  • Decreased heart rate
  • Dehydration
  • Diarrhea
  • Difficulty urinating
  • Dizziness
  • Frequent urination
  • Headache
  • Nausea
  • Respiratory depression

Cognitive effects

• • Cognitive euphoria
  • Compulsive redosing
• • Empathy, affection and sociability enhancement
  • Increased libido
  • Increased music appreciation
  • Motivation enhancement
• • Addiction suppression
  • Anxiety suppression
  • Disinhibition
  • Sleepiness
  • Thought deceleration

See also

• Responsible use
• Summary index
• Subjective effect index
• Psychoactive substance index