Tramadol/Summary

Main article: Tramadol

Psychoactive class: Opioids

Chemical class: Phenylpropylamine

Oral

• Thresh				Common				Heavy
  25	-	25	-	100	-	250	-	300	mg
  		Light				Strong

• • Total: 6 - 10 hours
  • Onset: 15 - 60 minutes
  • Come up: 30 - 60 minutes
  • Peak: 2 - 6 hours
  • Offset: 2 - 4 hours

Harm potential

• • Moderately addictive with a high potential for abuse
  • Low toxicity, potentially lethal when mixed with depressants like alcohol or benzodiazepines

Tolerance

• • Full tolerance is reached develops with prolonged and repeated use
  • Decreases to half after 3 - 7 days
  • Returns to baseline after 1 - 2 weeks
  • Cross-tolerance with all other opioids

Physical effects

• • Stimulation
• • Appetite suppression
  • Cough suppression
  • Pain relief
  • Sedation
• • Constipation
  • Dehydration
  • Difficulty urinating
  • Headache
  • Itchiness
  • Muscle twitching
  • Nausea
  • Restless legs
  • Seizure

Cognitive effects

• • Cognitive euphoria
  • Compulsive redosing
• • Empathy, affection and sociability enhancement
  • Increased music appreciation
  • Motivation enhancement
• • Anxiety suppression
  • Disinhibition

See also

• Responsible use
• Summary index
• Subjective effect index
• Psychoactive substance index