|Summary sheet: Selegiline|
|Common names||Selegiline, Deprenyl|
|Routes of Administration|
Selegiline is a drug mainly used for treatment of parkinson's disease and depression. In more recent years, it has been used as a nootropic drug.
- 1 History and culture
- 2 Chemistry
- 3 Pharmacology
- 4 Subjective effects
- 5 Toxicity and harm potential
- 6 Legal status
- 7 See also
- 8 External links
- 9 Literature
- 10 References
History and culture
This History and culture section is a stub.
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Selegiline is a phenethylamine
Selegiline exerts its action by inhibiting MAO-B, and at higher doses, MAO-A.
|This subjective effects section is a stub.|
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The effects listed below are based upon the subjective effects index and personal experiences of PsychonautWiki contributors. These effects should be taken with a grain of salt and will rarely (if ever) occur all at once, but heavier doses will increase the chances of inducing a full range of effects. Likewise, adverse effects become much more likely on higher doses and may include serious injury or death.
- If applicable, a brief paragraph summary of the substance's cognitive effects may be included here. You may select from a list of cognitive effects to add below here.
There are currently no anecdotal reports which describe the effects of this compound within our experience index. Additional experience reports can be found here:
Toxicity and harm potential
This toxicity and harm potential section is a stub.
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It is strongly recommended that one use harm reduction practices when using this substance.
Tolerance and addiction potential
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Although many psychoactive substances are reasonably safe to use on their own, they can quickly become dangerous or even life-threatening when taken with other substances. The following lists some known dangerous combinations, but cannot be guaranteed to include all of them. Independent research should always be conducted to ensure that a combination of two or more substances is safe to consume. Some interactions listed have been sourced from TripSit. Combinations with the following substances can cause dangerously high serotonin levels. Serotonin syndrome requires immediate medical attention and can be fatal if left untreated.
- MAOIs such as syrian rue, banisteriopsis caapi, 2C-T-7, αMT, phenelzine, selegiline, and moclobemide
- Serotonin releasers such as MDMA, 4-FA, methamphetamine, methylone and αMT
- Selective serotonin re-uptake inhibitors (SSRIs)
- Serotonin-norepinephrine reuptake inhibitors (SNRIs) such as tramadol and DXM
This legality section is a stub.
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- Selegiline (Wikipedia)
- Selegiline (Erowid Vault)
- Selegiline (TiHKAL / Isomer Design)
- L-Deprenyl (r/Nootropics FAQ)
- APA formatted reference
Please see the citation formatting guide if you need assistance properly formatting citations.
- Gillman, P. K. (2005). Monoamine oxidase inhibitors, opioid analgesics and serotonin toxicity. British Journal of Anaesthesia, 95(4), 434-441. https://doi.org/10.1093/bja/aei210