Talk:Alimemazine

This article is in the 'Talk' namespace because it is an unfinished draft. This section is used to host drafts for unpublished articles as well as discussions for published ones. If you'd like to use this area to discuss this draft, please do so in the 'Discussion' section at the very bottom of the page. This notice will be removed once this draft has been approved for publication by an administrator.

This page has not been fully approved by the PsychonautWiki administrators.

It may contain incorrect information, particularly with respect to dosage, duration, subjective effects, toxicity and other risks. It may also not meet PW style and grammar standards.

Summary sheet: Alimemazine

Alimemazine, also known as trimeprazine, is a phenothiazine derivative that acts as an antihistamine, a sedative, and an antiemetic. Alimemazine is used principally as an antiemetic to prevent motion sickness or as an antihistamine in combination with other medications in cough and cold preparations.

Although it is similair in structure to the phenothiazine antipsychotics and is in the same class of drugs as chlorpromazine and trifluoperazine it is not used as an antipsychotic.

It is commonly prescribed for the treatment of anxiety disorders, organic mood disorders, sleep disturbances, somatoform autonomic dysfunction and several neuroses

and is also used as a sedative for young children before an operation.

Chemical Nomenclature

Common names

Trimeprazine, Nedeltran, Panectyl, Repeltin, Therafene, Theraligene, Theralen, Theralene, Vallergan, Vanectyl, and Temaril

Substitutive name

Alimemazine

Systematic name

N,N,2-trimethyl-3-phenothiazin-10-yl-propan-1-amine

Class Membership

Psychoactive class

Depressant

Chemical class

Tartrate

Routes of Administration

WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section.

⇣ Oral
Dosage
Bioavailability	90%^{[citation needed]}
Threshold	2.5 mg
Light	5 - 15 mg
Common	20 - 25 mg
Strong	30 - 35 mg
Heavy	40 mg +
Duration
Total	8 - 12 hours
Onset	20 - 60 minutes
After effects	8 - 48 hours

DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy.

History and culture

This History and culture section is a stub.

As a result, it may contain incomplete or wrong information. You can help by expanding it.

Chemistry

This chemistry section is incomplete.

You can help by adding to it.

Pharmacology

This pharmacology section is incomplete.

You can help by adding to it.

Subjective effects

This subjective effects section is a stub.

As such, it is still in progress and may contain incomplete or wrong information.

You can help by expanding or correcting it.

Disclaimer: The effects listed below cite the Subjective Effect Index (SEI), an open research literature based on anecdotal user reports and the personal analyses of PsychonautWiki contributors. As a result, they should be viewed with a healthy degree of skepticism.

It is also worth noting that these effects will not necessarily occur in a predictable or reliable manner, although higher doses are more liable to induce the full spectrum of effects. Likewise, adverse effects become increasingly likely with higher doses and may include addiction, severe injury, or death ☠.

Physical effects

- Sedation - Alimemazine causes a very pronounced sedation and a general feeling of slowness, this effect is normally considerably stronger than most antihistamines and can be comparable to that of benzodiazepines in higher dosages.
- Physical euphoria
- Increased heart rate and increased blood pressure
- Abnormal heartbeat - This effect is rare.
- Nausea suppression - Alimemazine is used to treat motion sickness or nausea.

Cognitive effects

- Anxiety suppression - Alimemazine is commonly sold for anxiety disorders and panic disorders due to it's fast onset in liquid form.
- Euphoria - Usually, Alimemazine causes minimal euphoria normally only in anxious individuals.
- Delusions of sobriety - This is the false belief that one is perfectly sober despite obvious evidence to the contrary such as severe cognitive impairment and an inability to fully communicate with others. This effect can last up to 48 hours after ingestion.
- Sleepiness - Feelings of physical exhaustion and tiredness is a very pronounced effect of Alimemazine. The substance is therefore used to treat insomnia and abnormal sleep cycles.
- Confusion - This effect is less pronounced then that of other antihistamines such as Diphenhydramine and Promethazine.
- Dream potentiation

Experience reports

There are currently 0 experience reports which describe the effects of this substance in our experience index.

Additional experience reports can be found here:

Erowid Experience Vaults: Alimemazine

Toxicity and harm potential

This toxicity and harm potential section is a stub.

As a result, it may contain incomplete or even dangerously wrong information! You can help by expanding upon or correcting it.
Note: Always conduct independent research and use harm reduction practices if using this substance.

It is strongly recommended that one use harm reduction practices when using this substance.

Lethal dosage

Tolerance and addiction potential

Dangerous interactions

This dangerous interactions section is a stub.

As such, it may contain incomplete or invalid information. You can help by expanding upon or correcting it.

Warning: Many psychoactive substances that are reasonably safe to use on their own can suddenly become dangerous and even life-threatening when combined with certain other substances. The following list provides some known dangerous interactions (although it is not guaranteed to include all of them).

Always conduct independent research (e.g. Google, DuckDuckGo, PubMed) to ensure that a combination of two or more substances is safe to consume. Some of the listed interactions have been sourced from TripSit.

Legal status

This legality section is a stub.

As such, it may contain incomplete or wrong information. You can help by expanding it.

External links

(List along order below)

SUBSTANCE (Wikipedia)
SUBSTANCE (Erowid Vault)
SUBSTANCE ([PiHKAL or TiHKAL] / Isomer Design)

Literature

APA formatted reference

Please see the citation formatting guide if you need assistance properly formatting citations.

References