Talk:ΒOH-2C-B

Summary sheet: ΒOH-2C-B

Template:SubstanceBox/BOH-2C-B βOH-2C-B (also known as BOH-2C-B, beta-hydroxy 2C-B, or BOHB) is a novel psychedelic substance of the phenethylamine class. It is a structural analog of 2C-B.

Subjective effects include open and closed-eye visuals, time distortion, euphoria, and ego loss. Compared to 2C-B, its effects are often described as being more stimulating and less psychedelic with a significantly longer duration and reduced potency.

βOH-2C-B is perhaps three times less potent than 2C-B by weight, with normal recreational dosages reportedly ranging between 20-60mg. a It is thought to have a similarly steep dose-response curve to 2C-B. Theduration of action fo βOH-2C-B appears to be between 12-15 hours, with some users experience effects lasting well beyond the 16-hour mark.

βOH-2C-B is relatively uncommon and has little to no history of human usage prior to 2020 when it began to appear and be distributed by online vendors as a research chemical.

Very little data exists about the pharmacological properties, metabolism, and toxicity of βOH-2C-B. As a result, users are advised to approach this novel and poorly understood hallucinogenic substance with the proper amount of precaution and harm reduction practices if choosing to use it.

History and culture

Experience reports of βOH-2C-B began to appear on the internet circa 2020, following its appearance online by gray-market research chemical vendors.

βOH-2C-B is considered a relatively obscure substance, even among research chemicals. An analysis of the Google search history between 2004-2024 shows that βOH-2C-B was inconsistently searched for during this time (about 32 times less often than 2C-B).

Chemistry

βOH-2C-B, or beta-hydroxy 2C-B, is a substituted phenethylamine featuring a phenyl ring bound to an amino (NH₂) group through an ethyl chain. βOH-2C-B contains the structure of 2C-B substituted with a hydroxy group at the beta carbon of the structure (R₁). βOH-2C-B contains methoxy functional groups CH₃O- attached to carbons R₂ and R₅ as well as a bromine atom attached to carbon R₄ of the phenyl ring. βOH-2C-B belongs to the 2C family of phenethylamines which contain methoxy groups on the 2 and 5 positions of the benzene ring.

Pharmacology

Further information: Serotonergic psychedelic

βOH-2C-B likely acts as a 5-HT_2A partial agonist. The psychedelic effects are believed to come from its efficacy at the 5-HT_2A receptors. However, the role of these interactions and how they result in the psychedelic experience continues to remain elusive.

Subjective effects

This subjective effects section is a stub. As such, it is still in progress and may contain incomplete or wrong information. You can help by expanding or correcting it.

Disclaimer: The effects listed below cite the Subjective Effect Index (SEI), an open research literature based on anecdotal user reports and the personal analyses of PsychonautWiki contributors. As a result, they should be viewed with a healthy degree of skepticism.

It is also worth noting that these effects will not necessarily occur in a predictable or reliable manner, although higher doses are more liable to induce the full spectrum of effects. Likewise, adverse effects become increasingly likely with higher doses and may include addiction, severe injury, or death ☠.

Physical effects

• • Spontaneous tactile sensations
  • Increased heart rate
  • Nausea
  • Pupil dilation

Visual effects

• Enhancements

  • Colour enhancement
  • Pattern recognition enhancement
  • Visual acuity enhancement

  Distortions

  • Drifting (melting, breathing, morphing and flowing)
  • Colour shifting
  • Depth perception distortions
  • Perspective distortions
  • Symmetrical texture repetition
  • Tracers
  • After images
  • Brightness alteration
  • Diffraction

  Geometry

  Hallucinatory states

  • Transformations
  • Internal hallucination (autonomous entities; settings, sceneries, and landscapes; perspective hallucinations and scenarios and plots)

Cognitive effects

• • Conceptual thinking
  • Cognitive euphoria
  • Delusion
  • Emotion enhancement
  • Immersion enhancement
  • Increased music appreciation
  • Memory suppression
    • Ego death
  • Novelty enhancement
  • Personal bias suppression
  • Thought loops
  • Time distortion
  • Unity and interconnectedness

Auditory effects

• • Enhancements
  • Distortions
  • Hallucinations

Experience reports

There are no reports describing the effects of this compound within our experience index, but some experience reports can be found here:

• Erowid Experience Vaults: BOH-2C-B

Toxicity and harm potential

Further information: Research chemicals § Toxicity and harm potential, and Responsible use § Hallucinogens

The toxicity and long-term health effects of recreational βOH-2C-B use do not seem to have been studied in any scientific context and the exact toxic dose is unknown. This is because βOH-2C-B is a research chemical with very little history of human usage. Anecdotal evidence from people within the psychonaut community who have tried βOH-2C-B suggests that there are no negative health effects attributed to simply trying the substance by itself at low to moderate doses and using it very sparingly (but nothing can be completely guaranteed). Independent research should always be done to ensure that a combination of two or more substances is safe before consumption.

Some users have reported headaches and migraines towards the end of their βOH-2C-B experience, which may indicate a potential toxicity.

It is strongly recommended that one use harm reduction practices when using this substance.

Tolerance and addiction potential

As with psychedelics in general, βOH-2C-B is not habit-forming and the desire to use it can actually decrease with use. It is most often self-regulating.

Tolerance to the effects of βOH-2C-B are built almost immediately after ingestion. After that, it takes about 3 days for the tolerance to be reduced to half and 7 days to be back at baseline (in the absence of further consumption). βOH-2C-B presents cross-tolerance with all psychedelics, meaning that after the consumption of βOH-2C-B, all psychedelics will have a reduced effect.

Legal status

This legality section is a stub. As such, it may contain incomplete or wrong information. You can help by expanding it.

• Germany: βOH-2C-B is controlled under the NpSG (New Psychoactive Substances Act) as of November 26, 2016. Production and import with the aim to place it on the market, administration to another person and trading is punishable. Possession is illegal but not penalized.
• Netherlands: βOH-2C-B is a 2-phenethylamine ring-substituted derivative and thus falls under the 2024 analogue update to the Dutch Opium Act.
• United Kingdom: It is illegal to produce, supply, or import this drug under the Psychoactive Substance Act, which came into effect on May 26th, 2016.
• United States: βOH-2C-B is unscheduled in the U.S., but may be considered an analogue of 2C-B under the Federal Analogue Act and thus a Schedule I drug.{{https://www.folkhalsomyndigheten.se/nyheter-och-press/nyhetsarkiv/2019/april/atta-nya-amnen-klassas-som-narkotika/}}

See also

• Responsible use
• 2C-B
• 2C-x
• Bk-MDMA
• Phenethylamine
• Hallucinogen
• Psychedelics

External links

• βOH-2C-B (Wikipedia)
• βOH-2C-B (Isomer Design)
• Bk-2CB (Bluelight)