|Summary sheet: Magnesium|
Magnesium is a nootropic supplement available in many forms For tips on how to properly format a substance article, please refer to this document: Content Style Guide - Substance
- 1 History and culture
- 2 Chemistry
- 3 Pharmacology
- 4 Subjective effects
- 5 Toxicity and harm potential
- 6 Legal status
- 7 See also
- 8 External links
- 9 Literature
- 10 References
History and culture
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Magnesium acts as a voltage-dependent NMDA antagonist 
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Disclaimer: The effects listed below are cited from the Subjective Effect Index (SEI), which relies on assorted anecdotal reports and the personal experiences of PsychonautWiki contributors. As a result, they should be taken with a healthy amount of skepticism. It is worth noting that these effects will not necessarily occur in a consistent or reliable manner, although higher doses (common+) are more likely to induce the full spectrum of reported effects. Likewise, adverse effects become much more likely on higher doses and may include serious injury or death.
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There are currently no anecdotal reports which describe the effects of this compound within our experience index.
Toxicity and harm potential
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It is strongly recommended that one use harm reduction practices when using this substance.
Tolerance and addiction potential
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Although many psychoactive substances are reasonably safe to use on their own, they can quickly become dangerous or even life-threatening when combined with other substances. The list below includes some known dangerous combinations (although it cannot be guaranteed to include all of them). Independent research (e.g. Google, DuckDuckGo) should always be conducted to ensure that a combination of two or more substances is safe to consume. Some interactions listed have been sourced from TripSit.
- Stimulants - Magnesium can potentiate and reverse tolerance to stimulants, increasing the chance of adverse effects and overdose. This effect is sometimes used to prevent tolerance to stimulants and ADHD medications.
- Dissociatives - Magnesium can potentiate dissociative effects and may increase the chance of adverse effects or overdose.
- Opioids - Magnesium potentiates both the euphoric and sedative effects of opioids, which may result in adverse effects and overdose.
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