|Summary sheet: Magnesium|
Magnesium is a nootropic supplement available in many forms For tips on how to properly format a substance article, please refer to this document: Content Style Guide - Substance
History and culture
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Magnesium acts as a voltage-dependent NMDA antagonist 
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Disclaimer: The effects listed below cite the Subjective Effect Index (SEI), a research literature based on anecdotal reports and the personal experiences of PsychonautWiki contributors. As a result, they should be regarded with a healthy degree of skepticism. It is worth noting that these effects will not necessarily occur in a predictable or reliable manner, although higher doses are more liable to induce the full spectrum of effects. Likewise, adverse effects become much more likely with higher doses and may include addiction, serious injury, or death.
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There are currently no anecdotal reports which describe the effects of this compound within our experience index.
Toxicity and harm potential
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It is strongly recommended that one use harm reduction practices when using this substance.
Tolerance and addiction potential
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Although many psychoactive substances are reasonably safe to use on their own, they can suddenly become dangerous or even life-threatening when combined with other substances. The following list includes some known dangerous combinations (although it is not guaranteed to include all of them). Independent research (e.g. Google, DuckDuckGo) should always be conducted to ensure that a combination of two or more substances is safe to consume. Some of the listed interactions have been sourced from TripSit.
- Stimulants - Magnesium can potentiate and reverse tolerance to stimulants, increasing the chance of adverse effects and overdose. This effect is sometimes used to prevent tolerance to stimulants and ADHD medications.
- Dissociatives - Magnesium can potentiate dissociative effects and may increase the chance of adverse effects or overdose.
- Opioids - Magnesium potentiates both the euphoric and sedative effects of opioids, which may result in adverse effects and overdose.
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