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|Summary sheet: Passionflower|
History and culture
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This chemistry section is incomplete.
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Passiflora genus varies greatly in pharmacogicaly active components. Some contain β-carboline-based reversible MAO inhibition. Passiflora incarnata is widely used as a sleep-aid and neurosis OTC treatment. Mithridatum (talk) 15:40, 28 September 2021 (UTC)
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Passionflower is a GABAA & GABAB  agonist as well as a MAO(monoamine oxidase) inhibitor.
|This subjective effects section is a stub.|
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Disclaimer: The effects listed below cite the Subjective Effect Index (SEI), an open research literature based on anecdotal user reports and the personal analyses of PsychonautWiki contributors. As a result, they should be viewed with a healthy degree of skepticism.
It is also worth noting that these effects will not necessarily occur in a predictable or reliable manner, although higher doses are more liable to induce the full spectrum of effects. Likewise, adverse effects become increasingly likely with higher doses and may include addiction, severe injury, or death ☠.
- Color enhancement
- Visual acuity suppression
- Depth perception suppression - At high doses of passionflower, some users report their vision completely lacking depth perception
- Cognitive euphoria - This effect is mild
- Sleepiness - Due to this effect it is commonly used as a herbal sleep aid
- Empathy, affection, and sociability enhancement
- Anxiety suppression
- Dream potentiation
- Psychedelics - Passionflower is reported to have a strong synergy with psychedelics, greatly potentiating visual effects.
- Cannabis - Passionflower combined with cannabis is reported to enhance the visual effects and euphoria of cannabis.
There are currently no anecdotal reports which describe the effects of this compound within our experience index. Additional experience reports can be found here:
Toxicity and harm potential
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It is strongly recommended that one use harm reduction practices when using this substance.
Tolerance and addiction potential
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Warning: Many psychoactive substances that are reasonably safe to use on their own can suddenly become dangerous and even life-threatening when combined with certain other substances. The following list provides some known dangerous interactions (although it is not guaranteed to include all of them).
Always conduct independent research (e.g. Google, DuckDuckGo, PubMed) to ensure that a combination of two or more substances is safe to consume. Some of the listed interactions have been sourced from TripSit. Combinations with the following substances can cause dangerously high serotonin levels. Serotonin syndrome requires immediate medical attention and can be fatal if left untreated.
- MAOIs - Such as banisteriopsis caapi, syrian rue, phenelzine, selegiline, and moclobemide.
- Serotonin releasers - Such as MDMA, 4-FA, methamphetamine, methylone and αMT.
- SSRIs - Such as citalopram and sertraline
- SNRIs - Such as tramadol and venlafaxine
This legality section is a stub.
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- APA formatted reference
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- ↑ http://ndnr.com/insomniasleep-medicine/passionflower-and-lemon-balm/
- ↑ Gillman, P. K. (2005). "Monoamine oxidase inhibitors, opioid analgesics and serotonin toxicity". British Journal of Anaesthesia. 95 (4): 434–441. doi:10.1093/bja/aei210 . eISSN 1471-6771. ISSN 0007-0912. OCLC 01537271. PMID 16051647.