Risperidone

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Summary sheet: Risperidone
Risperidone
Molecular structure of Risperidone
Risperidone.svg
Chemical Nomenclature
Common names Risperdal
Substitutive name Risperidone
Systematic name 3-[2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one
Class Membership
Psychoactive class Antipsychotic
Chemical class Benzisoxazole
Routes of Administration

WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section.



Oral
Dosage
Threshold 0.25 - 0.5 mg
Light 0.5 - 1 mg
Common 1 - 3 mg
Strong 3 - 6 mg
Heavy 6 mg +
Duration
Total 12 - 20 hours
Onset 20 - 60 minutes
Peak 2 - 8 hours
Offset 2 - 4 hours
After effects 12 - 24 hours









DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy.

Risperidone (trade name Risperdal) is an atypical antipsychotic medication used to treat schizophrenia, biploar disorder and irritability caused by autism. It is sometimes used as a sedative to reduce the effects of psychedelics like LSD and to induce sleepiness. Benzodiazepines are also used for this purpose.

Chemistry

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Pharmacology

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Risperidone has a quite complex pharmacology, but its main mechanism of action is that it is a D2 dopaminergic receptor antagonist, meaning it blocks dopamine from binding to the receptor, meanwhile not activating it.[citation needed] It also blocks most of the serotonin receptors, being an inverse agonist at the 5-HT2A, 5-HT2B, and 5-HT2C serotonin receptors.[citation needed] Risperidone has the strongest affinity to the 5-HT2A receptor.[citation needed] On top of that, it acts as an irreversible antagonist at the 5-HT7 serotonin receptor. Its hypnotic effects come from the blockade of dopamine D2 receptors.

Subjective effects

The effects listed below are based upon the subjective effects index and personal experiences of PsychonautWiki contributors. The listed effects should be taken with a grain of salt and will rarely (if ever) occur all at once, but heavier doses will increase the chances and are more likely to induce a full range of effects. Likewise, adverse effects become much more likely on higher doses and may include injury or death.

Cognitive effects
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Toxicity and harm potential

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This toxicity and harm potential section is a stub.

As such, it may contain incomplete or even dangerously wrong information. You can help by expanding upon or correcting it.
We also recommend that you practice diligent independent research and the most thorough harm reduction practices when using this substance.

Legal issues

  • United Kingdom: Risperidone is available only through prescription.
  • United States: Risperidone is available only through prescription.
  • Australia: Risperidone is available only through prescription.

See also

External links

References

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