Risperidone

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Summary sheet: Risperidone
Risperidone
Risperidone.svg
Chemical Nomenclature
Common names Risperdal
Substitutive name Risperidone
Systematic name 3-[2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one
Class Membership
Psychoactive class Antipsychotic
Chemical class Benzisoxazole
Routes of Administration

WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section.



Oral
Dosage
Threshold 0.25 - 0.5 mg
Light 0.5 - 1 mg
Common 1 - 3 mg
Strong 3 - 6 mg
Heavy 6 mg +
Duration
Total 12 - 20 hours
Onset 20 - 60 minutes
Peak 2 - 8 hours
Offset 2 - 4 hours
After effects 12 - 24 hours









DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy.

Interactions


Risperidone (also known as Risperdal) is an atypical antipsychotic medication of the benzisoxazole chemical class. Risperidone is prescribed for bipolar disorder, autism, and psychotic disorders, such as in schizophrenia. It is sometimes used as a sedative to reduce the effects of psychedelics like LSD and to induce sleepiness. Benzodiazepines are also used for this purpose.

Chemistry

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Pharmacology

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Risperidone has a complex pharmacology, but its main mechanism of action is as a D2 dopaminergic receptor antagonist. This means that it blocks dopamine from binding to the receptor, meanwhile not activating it.[citation needed] It also blocks most of the serotonin receptors, being an inverse agonist at the 5-HT2A, 5-HT2B, and 5-HT2C serotonin receptors.[citation needed] Risperidone has the strongest affinity to the 5-HT2A receptor.[citation needed] On top of that, it acts as an irreversible antagonist at the 5-HT7 serotonin receptor. Its hypnotic effects come from the blockade of dopamine D2 receptors.

Subjective effects

Disclaimer: The effects listed below are cited from the subjective effect index, which is based on anecdotal reports and the personal experiences of PsychonautWiki contributors. As a result, they should be treated with a healthy degree of skepticism. It is worth noting that these effects will rarely (if ever) occur all at once, although higher doses will increase the chances of inducing a full range of effects. Likewise, adverse effects become much more likely on higher doses and may include serious injury or death.

Physical effects
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Cognitive effects
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Experience reports

There are currently no anecdotal reports which describe the effects of this compound within our experience index. Additional experience reports can be found here:

Toxicity and harm potential

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We also recommend that you conduct independent research and use harm reduction practices when using this substance.

Legal status

  • Australia: Risperidone is available only through prescription.[citation needed]
  • Germany: Risperidone is a prescription medicine, according to Anlage 1 AMVV.[1]
  • United Kingdom: Risperidone is available only through prescription.[citation needed]
  • United States: Risperidone is available only through prescription.[citation needed]

See also

External links

References

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