From PsychonautWiki
(Redirected from Risperdal)
Jump to: navigation, search

This article is a stub.

As such, it may contain incomplete or wrong information. You can help by expanding it.


This article requires proofreading.

As such, it may contain incorrect grammar, spelling, or punctuation.

Summary sheet: Risperidone
Chemical Nomenclature
Common names Risperdal
Substitutive name Risperidone
Systematic name 3-[2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one
Class Membership
Psychoactive class Antipsychotic
Chemical class Benzisoxazole
Routes of Administration

WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section.

Threshold 0.25 - 0.5 mg
Light 0.5 - 1 mg
Common 1 - 3 mg
Strong 3 - 6 mg
Heavy 6 mg +
Total 12 - 20 hours
Onset 20 - 60 minutes
Peak 2 - 8 hours
Offset 2 - 4 hours
After effects 12 - 24 hours

DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy.

Risperidone (also known as Risperdal) is an atypical antipsychotic medication of the benzisoxazole chemical class. Risperidone is prescribed for bipolar disorder, autism, and psychotic disorders, such as in schizophrenia. It is sometimes used as a sedative to reduce the effects of psychedelics like LSD and to induce sleepiness. Benzodiazepines are also used for this purpose.



This chemistry section is incomplete.

You can help by adding to it.


Pill bottle-o.png

This pharmacology section is incomplete.

You can help by adding to it.

Risperidone has a complex pharmacology, but its main mechanism of action is as a D2 dopaminergic receptor antagonist. This means that it blocks dopamine from binding to the receptor, meanwhile not activating it.[citation needed] It also blocks most of the serotonin receptors, being an inverse agonist at the 5-HT2A, 5-HT2B, and 5-HT2C serotonin receptors.[citation needed] Risperidone has the strongest affinity to the 5-HT2A receptor.[citation needed] On top of that, it acts as an irreversible antagonist at the 5-HT7 serotonin receptor. Its hypnotic effects come from the blockade of dopamine D2 receptors.

Subjective effects

The effects listed below are based upon the subjective effects index and personal experiences of PsychonautWiki contributors. These effects should be taken with a grain of salt and will rarely (if ever) occur all at once, but heavier doses will increase the chances of inducing a full range of effects. Likewise, adverse effects become much more likely on higher doses and may include serious injury or death.

Cognitive effects

Toxicity and harm potential


This toxicity and harm potential section is a stub.

As such, it may contain incomplete or even dangerously wrong information. You can help by expanding or correcting it.
We also recommend that you conduct independent research and use harm reduction practices when using this substance.

Legal status

  • United Kingdom: Risperidone is available only through prescription.
  • United States: Risperidone is available only through prescription.
  • Australia: Risperidone is available only through prescription.

See also

External links


Question book-new.svg

This article does not cite enough references.

You can help by adding some.