Classical psychedelic

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The term classical psychedelic (or classic psychedelic) is an informal term that refers to the most common and historically significant psychedelic substances. Included in this list are LSD, psilocybin mushrooms, DMT, and mescaline.

A common feature of classical psychedelics is that they act as (partial) agonists at the serotonin 5-HT2A receptor, which is abundant in specific regions of the human brain.[1][2]

See also

References

  1. Carhart-Harris RL, Leech R, Hellyer PJ, Shanahan M, Feilding A, Tagliazucchi E, Chialvo DR and Nutt D (2014), The entropic brain: a theory of conscious states informed by neuroimaging research with psychedelic drugs. Front. Hum. Neurosci. 8:20. https://doi.org/10.3389/fnhum.2014.00020 (Open Access)
  2. Glennon, R. A., Titeler, M., and McKenney, J. D. (1984). Evidence for 5-HT2 involvement in the mechanism of action of hallucinogenic agents. Life Sci. 35, 2505–2511. https://doi.org/10.1016/0024-3205(84)90436-3