Talk:Withania somnifera (botany)

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Withania somnifera
Withania somnifera-3.jpg
An ashwagandha plant found in nature.
Taxonomical nomenclature
Kingdom Plantae
Unranked Angiosperms
Unranked Eudicots
Unranked Asterids
Order Solanales
Family Solanaceae
Genus Withania
Species W. somnifera
Common nomenclature
Common names Ashwagandha, Indian ginseng, Poison gooseberry and Winter cherry
Constituents
Active constituents Tropine, withanolides, cuscohygrine

Withania somnifera (Commonly known as Ashwagandha, Indian ginseng, Poison gooseberry and Winter cherry) is an adaptogenic[1] plant in the Solanaceae or Nightshade family that is used as a herbal treatment in Ayurvedic medicine. Ashwagandha contains flavonoids such as Withanolide A and Withaferin-A, which are believed to be responsible for Ashwagandha's psychoactive properties.

Ashwagandha has been well-researched for a multitude of health benefits, including anxiety reduction[2], stress reduction[3], physical performance enhancing[4][5], depression relief[6], and fatigue relief[7].

Chemistry

Molecule.svg

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Withanolides are present in all plants in the Solanaceae family of plants[citation needed], of which Withania Somnifera(Ashwagandha) is the highest in concentrations. These Withanolides are believed to be the prime component of Ashwagandha's psychoactive profile.[8]There has been reported to be high variability in the amount of active withanolides in common nutritional supplements, which may be due to lack of standardization of root powder.


Pharmacology

Chemical structure of Withanolides found in Ashwagandha

Subjective effects

The effects listed below are based upon the subjective effect index and personal experiences of PsychonautWiki contributors. The listed effects will rarely (if ever) occur all at once, but heavier dosages will increase the chances and are more likely to induce a full range of effects.

Physical effects

Cognitive effects

Experience reports

There are currently no anecdotal reports which describe the effects of this compound within our experience index. Additional experience reports can be found here:

Toxicity and harm potential

It is strongly recommended that one use harm reduction practices when using this drug.

Tolerance and addiction potential

Ashwaghanda is not habit-forming.

Legal issues

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This legality section is a stub.

As such, it may contain incomplete or wrong information. You can help by expanding it.

See also

External links

References

  1. Withania somnifera: an Indian ginseng. |http://www.ncbi.nlm.nih.gov/pubmed/17959291
  2. Naturopathic care for anxiety: a randomized controlled trial ISRCTN78958974. | http://www.ncbi.nlm.nih.gov/pubmed/19718255
  3. A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults. | http://www.ncbi.nlm.nih.gov/pubmed/23439798
  4. Effects of Withania somnifera (Ashwagandha) and Terminalia arjuna (Arjuna) on physical performance and cardiorespiratory endurance in healthy young adults. | http://www.ncbi.nlm.nih.gov/pubmed/21170205
  5. Examining the effect of Withania somnifera supplementation on muscle strength and recovery: a randomized controlled trial.| http://www.ncbi.nlm.nih.gov/pubmed/26609282
  6. A double-blind, placebo-controlled evaluation of the anxiolytic efficacy of an ethanolic extract of withania somnifera. | http://www.ncbi.nlm.nih.gov/pubmed/21407960
  7. Naturopathic care for anxiety: a randomized controlled trial ISRCTN78958974. | http://www.ncbi.nlm.nih.gov/pubmed/19718255
  8. A standardized root extract of Withania somnifera and its major constituent withanolide-A elicit humoral and cell-mediated immune responses by up regulation of Th1-dominant polarization in BALB/c mice. | https://www.ncbi.nlm.nih.gov/pubmed/17336338