Talk:Ginkgo Biloba

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Talk: Ginkgo Biloba

Summary sheet: Ginkgo Biloba

Ginkgo biloba, commonly known as ginkgo or gingko, also known as the maidenhair tree, is a species of tree native to China used as medicine. The tree was cultivated early in human history and remains commonly planted. Usually taken orally, as an extract in a capsule or pressed pill, or infusing the leaves in hot water to drink it as a tea. Adults have used between 120 and 240 milligrams a day in divided doses. It appears to take 4 to 6 weeks before improvements are noticed, also it have an immediate effect.

Ginkgo leaf extract is commonly used as a dietary supplement, but there is no scientific evidence that it supports human health or is effective against any disease.

Ginkgo Biloba
Chemical Nomenclature
Common names	DMT, Dimethyltryptamine, Dmitri
Substitutive name	N,N-Dimethyltryptamine
Systematic name	2-(1H-Indol-3-yl)-N,N-dimethylethanamine
Class Membership
Psychoactive class	Psychedelic
Chemical class	Tryptamine
Routes of Administration
WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section. ⇣ Oral Dosage Bioavailability x% - y% Threshold x - mg Light x - y mg Common x - y mg Strong x - y mg Heavy x mg + Duration Total x - y hours Onset x - y minutes Come up x - y minutes Peak x - y hours Offset x - y hours After effects x - y hours ⇣ Sublingual Dosage Bioavailability x% - y% Threshold x - mg Light x - y mg Common x - y mg Strong x - y mg Heavy x mg + Duration Total a - b hours Onset a - b minutes Come up a - b minutes Peak a - b hours Offset a - b hours After effects a - b hours DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy.

History and culture

The ginkgo leaf is the symbol of the Urasenke school of Japanese tea ceremony. The tree is the official tree of the Japanese capital of Tokyo, and the symbol of Tokyo is a ginkgo leaf. Since 1948, the badge of Tokyo University has been two ginkgo leaves (designed by Shoichi Hoshino), which became the university logo in 2004 with a redesign. The logo of Osaka University has been a simplified ginkgo leaf since 1991 when designer Ikko Tanaka created it for the university's sixtieth anniversary.

This History and culture section is a stub. As a result, it may contain incomplete or wrong information. You can help by expanding it.

Chemistry

This chemistry section is incomplete. You can help by adding to it.

The active compounds in ginkgo are Bilobalide, Ginkgoic acid, Ginkgolide-A, Ginkgotoxin (a neurotoxin that in large amounts can cause seizures. Is found in ginkgo seeds and, to a lesser extent, ginkgo leaves), Isorhamnetin, Amentoflavone, Ginkgetin, others...

Pharmacology

This pharmacology section is incomplete. You can help by adding to it.

Ginkgo biloba supplements have been shown to increase dopamine levels in animal and test-tube studies. Both ginkgolides and bilobalide inhibit GABA(A) receptors, with bilobalide demonstrating a more potent effect. Ginkgo biloba Extract (GbE) Restores Serotonin and Leptin Receptor Levels and Plays an Antioxidative Role in the Hippocampus of Ovariectomized Rats.

Subjective effects

This subjective effects section is a stub. As such, it is still in progress and may contain incomplete or wrong information. You can help by expanding or correcting it.

Disclaimer: The effects listed below cite the Subjective Effect Index (SEI), an open research literature based on anecdotal user reports and the personal analyses of PsychonautWiki contributors. As a result, they should be viewed with a healthy degree of skepticism.

It is also worth noting that these effects will not necessarily occur in a predictable or reliable manner, although higher doses are more liable to induce the full spectrum of effects. Likewise, adverse effects become increasingly likely with higher doses and may include addiction, severe injury, or death ☠.

Physical effects

• If applicable, a brief paragraph summary of the substance's physical effects may be included here. You may select physical effects to add below here.
  • Vasodilation Improved blood circulation
  • Decreased blood pressure
  • Decreased platelet aggregation
  • Stimulation Mild
  • Seizure enhancement Ginkgotoxin seems to alter a chemical signaling pathway in ways that may trigger epileptic seizures, see Chemistry info.

Visual effects

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  Enhancements

  • Visual acuity effect1

  Distortions

  • Visual distortion effect1

  Geometry

  If applicable, a brief paragraph summary describing the visual geometry produced by the substance may be included here.

  Hallucinatory states

  If applicable, a brief summary of the substance's visual effects profile may be written here.

  • Hallucinatory states1

Cognitive effects

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  • Analysis enhancementIt's mild, not comparable to Adderall.
  • Focus enhancementMild, not comparable to common stimulants...
  • StimulationMild.
  • Anxiety supressionReduces stress too and improve sleep.
  • Motivation enhancementMild.
  • Increased libidoIt can help with Erectile Dysfunction because of the improvements in blood flow.
  • StimulationMild.
  • Emotion enhancementImproved mood .
  • Memory enhancementUsed in Alzheimer desease.
  • Thought accelerationMild' .

Auditory effects

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  • Auditory effect1
  • Auditory effect2

Multi-sensory effects

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  • Multisensory effect1
  • Multisensory effect2

Transpersonal effects

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  • Transpersonal effect1
  • Transpersonal effect2

Experience reports

There are currently 0 experience reports which describe the effects of this substance in our experience index.

Additional experience reports can be found here:

• Erowid Experience Vaults: SUBSTANCE

Toxicity and harm potential

This toxicity and harm potential section is a stub. As a result, it may contain incomplete or even dangerously wrong information! You can help by expanding upon or correcting it. Note: Always conduct independent research and use harm reduction practices if using this substance.

Side effects of using ginkgo supplements may include increased risk of bleeding, gastrointestinal discomfort, nausea, vomiting, diarrhea, headaches, dizziness, heart palpitations, and restlessness, but this never happened to me in my experience using an extract daily for a year. Although use of standardized Ginkgo biloba leaf extracts in moderate amounts appears to be safe, excessive use may have undesirable effects, especially in terms of drug interactions. The dosing of anticoagulants, such as warfarin or antiplatelet medication, may be adversely affected by using ginkgo supplements

It is strongly recommended that one use harm reduction practices when using this substance.

If you are older, have a bleeding disorder or are pregnant, don't take ginkgo. The supplement might increase your risk of bleeding. If you're planning to have surgery, stop taking ginkgo two weeks beforehand.

In an open trial ginkgo biloba, an extract derived from the leaf of the Chinese ginkgo tree and noted for its cerebral enhancing effects, was found to be 84% effective in treating antidepressant-induced sexual dysfunction predominately caused by selective serotonin reuptake inhibitors

There is weak preliminary evidence for ginkgo affecting dementia[70][71] and tardive dyskinesia symptoms in people with schizophrenia.

Several studies show that ginkgo has a positive effect on memory and thinking in people with Alzheimer disease or vascular dementia.

Dangerous interactions

This dangerous interactions section is a stub. As such, it may contain incomplete or invalid information. You can help by expanding upon or correcting it.

Warning: Many psychoactive substances that are reasonably safe to use on their own can suddenly become dangerous and even life-threatening when combined with certain other substances. The following list provides some known dangerous interactions (although it is not guaranteed to include all of them).

Always conduct independent research (e.g. Google, DuckDuckGo, PubMed) to ensure that a combination of two or more substances is safe to consume. Some of the listed interactions have been sourced from TripSit.

Legal status

This legality section is a stub. As such, it may contain incomplete or wrong information. You can help by expanding it.

See also

• Responsible use

External links

(List along order below)

• SUBSTANCE (Wikipedia)
• SUBSTANCE (Erowid Vault)
• SUBSTANCE ([PiHKAL or TiHKAL] / Isomer Design)

Literature

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