Dosage independent intensity

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Dosage independent intensity can be described as the particularly rare and inconsistent experience of spontaneously amplified psychedelic effects which are extremely disproportionate to the dosage consumed. For example, a user may ingest a threshold dosage but spontaneously experience high intensity effects such as moderate to overwhelming geometry, distortions, hallucinatory states, spirituality enhancement, and even ego death.

This experience can often feel like a defiance of normal pharmacology, it usually takes the user by surprise and most commonly occurs during the peak of the trip. Individuals who experience this effect often describe it as being very profound and intense due to its unexpected and spontaneous nature. It is also worth noting that this effect seems to primarily happen to users who are already somewhat experienced with the substance being consumed.

Dosage independent intensity is most commonly induced under the influence of mild dosages of psychedelic tryptamine compounds, such as ayahuasca, psilocybin, 4-AcO-DMT, and DMT.

Psychoactive substances

Compounds within our psychoactive substance index which may cause this effect include:

See also