Tianeptine/Summary

Main article: Tianeptine

Psychoactive class: Antidepressant

Chemical class: Tricyclic antidepressant

Oral

• Thresh				Common				Heavy
  3	-	6	-	12	-	35	-	100	mg
  		Light				Strong

• • Total: 2 - 3 hours
  • Onset: 30 - 60 minutes
  • Come up: 15 - 30 minutes
  • Peak: 60 - 90 minutes

Harm potential

• • Mildly addictive
  • Large therapeutic index and margin of safety

Tolerance

• • Full tolerance is reached with prolonged use
  • Decreases to half after 3 - 7 days
  • Returns to baseline after 1 - 2 weeks
  • Cross-tolerance with trycyclic antidepressants and opioids

Physical effects

• • Stimulation
• • Constipation
  • Dizziness
  • Headache
  • Physical fatigue

Visual effects

• • Internal hallucination

Cognitive effects

• • Cognitive euphoria
• • Focus enhancement
  • Motivation enhancement
  • Thought acceleration
• • Anxiety suppression
  • Cognitive fatigue
  • Thought deceleration

See also

• Responsible use
• Summary index
• Subjective effect index
• Psychoactive substance index