Tianeptine/Summary
Psychoactive class: Antidepressant
Chemical class: Tricyclic antidepressant
Harm potential

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- Mildly addictive
- Large therapeutic index and margin of safety
Tolerance

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- Full tolerance is reached with prolonged use
- Decreases to half after 3 - 7 days
- Returns to baseline after 1 - 2 weeks
- Cross-tolerance with trycyclic antidepressants and opioids