Talk:Olanzapine

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initial draft. This will contain a myriad of information and will be formatted later :) --Corticosteroid (talk) 22:58, 20 October 2017 (CEST)

Structure of olanzapine.
A five milligram tablet of olanzapine manufactured by Apotex. This tablet is designed to dissolve in the mouth and be absorbed through the blood vessels inside of the mouth.

Olanzapine, first branded as Zyprexa, is a widely-used antipsychotic substance of the thienobenzodiazepine chemical class. It produces sedating and neuroleptic effects when administered. Olanzapine can be given by mouth and can also be injected into a muscle. Olanzapine might be useful as a trip aborter, especially for stimulants, as it blocks the action of dopamine. [citation needed]

Chemistry

Olanzapine is a thienobenzodiazepine. It includes a piperazine moiety at R4.

Pharmacology

Olanzapine is known to cause weight gain and induce diabetes mellitus type 2 more frequently than other antipsychotics. However, it is less likely to produce tardive dyskinesia or an extrapyramidal reaction. It appears to be an effective treatment for schizophrenia.[1]

Subjective effects

Physical effects
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Cognitive effects
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not the crème de là crème

(doses:
Light: 2.5 mg
Medium: 5 to 7.5 mg
Heavy: 10 mg
Strong: 10 mg +)

External links

References

  1. Leucht, S., Cipriani, A., Spineli, L., Mavridis, D., Örey, D., Richter, F., ... & Kissling, W. (2013). Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis. The Lancet, 382(9896), 951-962.