|Summary sheet: Metonitazene|
Metonitazene is an analgesic drug related to etonitazene, which was first reported in 1957, and has been shown to have approximately 100 times the potency of morphine by central routes of administration, but if used orally it has been shown to have approximately 10 times the potency of morphine.
Its effects are similar to other opioids like fentanyl and heroin, including analgesia, euphoria, sleepiness. Adverse effects include vomiting, and respiratory depression that can potentially be fatal. Because of high dependency potential and dangerous adverse effects it has never been introduced in pharmacotherapy.
|Common names||DMT, Dimethyltryptamine, Dmitri|
|Routes of Administration|
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Disclaimer: The effects listed below cite the Subjective Effect Index (SEI), a research literature based on anecdotal reports and the personal experiences of PsychonautWiki contributors. As a result, they should be regarded with a healthy degree of skepticism. It is worth noting that these effects will not necessarily occur in a predictable or reliable manner, although higher doses are more liable to induce the full spectrum of effects. Likewise, adverse effects become much more likely with higher doses and may include addiction, serious injury, or death.
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- Sedation - Metonitazene can result in overwhelming feelings of sedation and tiredness and is considered more sedating than Etazene.
- Respiratory depression - In comparison to other opiates, metonitazene displays this effect at lower doses relative to euphoria then other opiates, and even at low doses results in the sensation that the breath is slowed down mildly to moderately, but does not cause noticeable impairment. At high doses and overdoses, opioid-induced respiratory depression can result in a shortness of breath, abnormal breathing patterns, semi-consciousness, or unconsciousness. Severe overdoses can result in a coma or death without immediate medical attention.
- Physical euphoria - This substance can be considered as less intense in its physical euphoria when compared with that of Etazene or diacetylmorphine (heroin). It is still however capable of extreme feelings of intense physical comfort, warmth and bliss which spreads throughout the body.
- Nasal damage - Generally metonitazene is considered to be highly acidic, with reports of a PH as low as 2. As a result this substance is exceedingly caustic to the nasal cavities and highly unpleasant to insufflate. Some users report mixing a small amount of baking soda to a solution of metonitazene and water to lower its PH thus make it less painful to consume. Nevertheless, It is recommended to perform a sterile saline nasal rinse 15 minutes after snorting this substance. Even with that precaution, intranasal use without significant breaks to allow the nasal cavities to repair themselves will likely still damage the nasal mucous membranes. It is unknown whether this results in permanent injury or simply acute damage.
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Toxicity and harm potential
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It is strongly recommended that one use harm reduction practices when using this substance.
Tolerance and addiction potential
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Although many psychoactive substances are reasonably safe to use on their own, they can suddenly become dangerous or even life-threatening when combined with other substances. The following list includes some known dangerous combinations (although it is not guaranteed to include all of them). Independent research (e.g. Google, DuckDuckGo) should always be conducted to ensure that a combination of two or more substances is safe to consume. Some of the listed interactions have been sourced from TripSit.
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