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Summary sheet: Domperidone
Chemical Nomenclature
Common names Motilium
Substitutive name Domperidone, Domperidon
Systematic name 5-Chloro-1-(1-[3-(2-oxo- 2,3-dihydro-1H- benzo[d]imidazol-1- yl)propyl]piperidin-4-yl)-1H- benzo[d]imidazol-2(3H)- one
Class Membership
Psychoactive class Antiemetic
Chemical class Benzimidazole
Routes of Administration

WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section.

Common 10-80 mg
Total 4 - 7 hours
Onset 30 - 90 minutes
Peak 1 - 2 hours
Offset 2 - 4 hours

DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy.

Domperidone (also known as domperidon or motilium) is a medication used for a variety of purposes such as an antiemetic, gastroprokinetic agent and prolactinergic drug. Is has only limited history as a street drug, where it was distributed several times in Europe, especially in Switzerland, as a substitute in MDMA tablets. It is considered to have weak sedative effects. It lacks recreational value and is thus pretty much unknown within the recreational drug using community.



This chemistry section is incomplete.

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This pharmacology section is incomplete.

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Subjective effects

This subjective effects section is a stub.

As such, it is still in progress and may contain incomplete or wrong information.

You can help by expanding or correcting it.

Disclaimer: The effects listed below cite the Subjective Effect Index (SEI), an open research literature based on anecdotal user reports and the personal analyses of PsychonautWiki contributors. As a result, they should be viewed with a healthy degree of skepticism.

It is also worth noting that these effects will not necessarily occur in a predictable or reliable manner, although higher doses are more liable to induce the full spectrum of effects. Likewise, adverse effects become increasingly likely with higher doses and may include addiction, severe injury, or death ☠.

Physical effects

Cognitive effects

Toxicity and harm potential


This toxicity and harm potential section is a stub.

As a result, it may contain incomplete or even dangerously wrong information! You can help by expanding upon or correcting it.
Note: Always conduct independent research and use harm reduction practices if using this substance.

Legal issues

  • United Kingdom: The drug is available as a prescription medication.
  • United States: Domperidone is not approved for sale in the US.
  • Australia: The substance is available only through prescription.

See also

External links