Metizolam/Summary
		
		
		
		
		
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Harm potential 
     
    
Tolerance 
     
    
    
		
	
Harm potential  
    
    - 
- Extremely addictive
- Large therapeutic index and margin of safety
 
Tolerance  
    
    - 
- Full tolerance is reached within a couple of days of repeated administration
- Decreases to half after 3 - 7 days
- Returns to baseline after 1 - 2 weeks
- Cross-tolerance with all thienzodiazepines and benzodiazepines