From PsychonautWiki
Jump to navigation Jump to search

This page has not been fully approved by the PsychonautWiki administrators.

It may contain incorrect information, particularly with respect to dosage, duration, subjective effects, toxicity and other risks. It may also not meet PW style and grammar standards.


This article is a stub.

As such, it may contain incomplete or wrong information. You can help by expanding it.

Ondansetron, sold under the brand name Zofran among others, is a medication used to prevent nausea and vomiting normally caused by cancer chemotherapy, radiation therapy, or surgery, however it's ineffective in treating vomiting caused by motion sickness. It's also effective for treating gastroenteritis, which is inflammation of the gastrointestinal tract, stomach, and small intestine. It is a serotonin 5-HT3 receptor antagonist and does not have any effect on dopamine or muscarinic receptors. It can be taken by mouth or by injection into a muscle or vein.

Common side effects include diarrhea, constipation, headache, sleepiness, and itchiness. Serious side effects included QT prolongation and severe allergic reaction. It appears to be safe during pregnancy but this has not been studied well.