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Anahuasca, or ayahuasca-analog is a blanket term for any combination of compounds that contain an MAOI, meant to produce psychedelic-like effects, meant to be ingested orally. As opposed to smoked combinations. See: Changa
The term ayahausca analog appears (to) have been coined by Dennis McKenna. The American ethnobotanist Jeremy Bigwood was probably the first person to test pharmahuasca (100 mg each of harmaline hydrochloride and N,N-DMT) on himself; he reported "DMT-like hallucinations" (Ott 1994, 52). The chemist and chaos theorist Mario Markus used the Heffter Technique (self-experimentation) to perform extensive experiments into the optimal proportions for mixing the alakaloids.
The fundamental idea behind this, seems to be the combination of a Psychoactive Substance, and an MAOI. There are many natural resources of Harmaline and Harmine containing plants. Harmala alkaloids Seem to be the most common, but any MAOI can be used. Shortly after the ingestion of the MAOI (usually 15- 20 minutes) a psychoactive substance or plant is consumed.
Because the effects of these blends can be extremely unpleasant, people are generally warned against using them. Dosages are for one person, preparation can be found here: Preparation
For pharmahuasca, 100 mg N,N-DMT and 50 mg harmaline is usually the recommended dosage per person. However, combinations of 50 mg harmaline, 50 mg harmine, and 50 mg, N,N-DMT have also been tested with success. As a rule, the fewer the β-carbolines, the less the nausea; the more DMT, the more spectacular the visions. The constituents are put into separate gelatin capsules. The capsules with Harmaline/Harmine are swallowed first and the capsule containing the DMT is taken some fifteen to twenty minutes later. The purely synthetic MAO inhibitor Marplan is also suitable in place of harmaline and harmine
Classic Ayahuasca Analog
- 25 g Psychotria viridis leaves, dried and ground
- 3 g Peganum harmala seeds, crushed
Jerumahuasca or Mimosahuasca
Connoisseurs consider this ayahausca analog to be both the most easily tolerated and the most psychoactive preparation.
- 3 g Peganum harmala seeds, finely ground
- 9 g Mimosa tenuiflora root cortex
Prairie Ayahuasca (Prairiehuasca)
This blend is especially popular in North America. Predominantly pleasant experiences have been reports (ott 1994, 63; cf. DeKorne 1994, 97).
- 3-4 g Peganum harmala seeds, finely ground
- 30 g Desmanthus illinoensis root cortex (prairie mimosa, Illinois bundleweed, Illinois bundleflower)
This blend is especially popular in Australia and has been used with good success.
- 3 g Peganum harmala seeds, finely ground
- 20 g Acacia phlebophylla leaves, ground (cf. Acacia spp.)
This preparation is a combination of Peganum harmala and Lophophora williamsii. It may be pharmacologically very dangerous.
San Pedro Ayahuasca (Perdohuasca)
The following amounts and ingredients have been reported to produce pleasant effects (in Entheogene 5 . 53).
- 1-3 g Syrian rue (Peganum harmala)
- 20-25 g San Pedro cactus powder (see Trichocereus pachanoi)
This blend may be pharmacologically dangerous.
This mixture, which is also known as mushroom ayahuasca or soma ayahuasca consists of:
- 3 g Peganum harmala and 3 g mushrooms (Psilocybe cubensis)
- 2 g Peganum harmala and 1.5 g Psilocybe semilanceata in sage tea
Although the report (in Entheogene 5 :40 f.) spoke of quite pleasant experiences, this mixture appears to be potentially dangerous.
- 3 g Peganum harmala
- 1 Argyreia nervosa seed
- 3-4 g Desmanthus illinoensis root cortex
For several years there has been considerable speculation that the pre-Columbian Maya may have used a psychoactive ritual drink that was an ayahuasca analog. It has been conjectured that the Mayans used a Banisteriopsis species that grows in the Mesoamerican lowlands in combination with a source of DMT to make "mayahuasca" (Hyman 1994). It is entirely possible that Banisteriopsis miricata was used for this purpose, as its stems contain harmine and its leaves DMT. In other words, it is possible that an ayahuasca analog was made from just one plant.
The pharmacologist James Callaway has hypothesized that under certain circumstances a kind of pharmahuasca (which he calls endohuasca) is produced in the brain when both endogenous β-carbolines and endogenous DMT are excreted. This endohuasca produces dreams in a neurochemical manner (Callaway 1995; cf. also Ott 1996).
Some drug combinations be be dangerous (See: Dangerous Drug Combinations, a person without proper understanding of the chemicals they are injesting could cause harm to themselves.