Talk:5-MeO-DMT

worth including warning panel about not consuming this with a MAOI? Lots of evidence that suggests it is dangerous and can potentially kill you Clarity (talk) 01:38, 22 November 2016 (CET)Clarity

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Thanks for pointing this out! I don't think this should have a warning panel because the risk for the average person is not high enough since the majority of people are not taking MAOIs. In my opinion, warning panels should be used as sparingly as possible because I think that people will ignore them if there are too many warnings. I will, however, add this information to the introduction paragraph, the substance box in red text alongside the dosage information, and the harm potential section.

--Oskykins (talk) 07:06, 22 November 2016 (CET)

Sounds reasonable to me =]

-- Clarity (talk) 21:17, 22 November 2016

O-methyl-bufotenin

I think it would be worthwhile to add O-methyl-bufotenin and OMBT as alternative names for 5-MeO-DMT. They’re not at all in widespread usage, but since bufotenin is a far lesser known drug, trying to slowly phase them into existence could eventually stem the tide of people trying 5-MeO-DMT believing it to be analogous to DMT. People also have a far easier time remembering 4 characters than 7. 5-CNT-FAI (talk) 01:50, 12 September 2022 (UTC)

5-HT receptors

The pharmacology section says:

"5-Meo-DMT's psychedelic effects are primarily believed to come from its efficacy at the 5-HT2A receptor as a partial agonist. Specifically, this molecule shows high binding affinity for the 5-HT2A and 5-HT1A subtypes."

This is confusing for my. How is the 5-HT1A receptor a subtype of the 5-HT2A receptor?

Also, the Wikipedia entry on 5-MeO-DMT specifies that the effect on the 5-HT1A receptor is about a 1000 times stronger than that on the 5-HT2A receptor (which I believe is the one LSD and psilocybin bind to. Shouldn't this be added here? --Mircea (talk) 14:30, 30 June 2024 (UTC)