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Summary sheet: 3-CPM
Chemical Nomenclature
Common names DMT, Dimethyltryptamine, Dmitri
Substitutive name N,N-Dimethyltryptamine
Systematic name 2-(1H-Indol-3-yl)-N,N-dimethylethanamine
Class Membership
Psychoactive class Psychedelic
Chemical class Tryptamine
Routes of Administration

WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section.

Bioavailability x% - y%[1]
Threshold x - mg
Light x - y mg
Common x - y mg
Strong x - y mg
Heavy x mg +
Total x - y hours
Onset x - y minutes
Come up x - y minutes
Peak x - y hours
Offset x - y hours
After effects x - y hours

Bioavailability x% - y%
Threshold x - mg
Light x - y mg
Common x - y mg
Strong x - y mg
Heavy x mg +
Total a - b hours
Onset a - b minutes
Come up a - b minutes
Peak a - b hours
Offset a - b hours
After effects a - b hours

DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy.

3-Chlorophenmetrazine (also known as 3C-Phenmetrazine, PAL-594, and 3-CPM) is a novel stimulant substance of the phenylmorpholine class.3-Chlorophenmetrazine (3-CPM) is a substance derived from phenmetrazine, a stimulant that was once used as an appetite suppressant in Europe during the 1950s. Its primary action involves increasing the levels of neurotransmitters like serotonin, dopamine, and norepinephrine in the brain.

Use of 3-CPM commonly results in effects such as heightened alertness, improved focus and motivation, accelerated thoughts, and a sense of euphoria. Many individuals compare the effects of 3-CPM to those of amphetamines, which are also stimulants. Notably, users often describe 3-CPM as producing a milder and more controlled stimulant effect when compared to other stimulants. This characteristic makes it a popular choice for aiding study efforts or enhancing productivity.

However, there is limited information available regarding the pharmacological properties, metabolism, and potential harm associated with 3-CPM. Due to this lack of knowledge, it is strongly advised for those considering the use of this substance to employ harm reduction practices to ensure their safety.

History and culture

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3-Chlorophenmetrazine is based on the once-popular appetite suppressant phenmetrazine. Phenmetrazine, initially synthesized in the 1940s, exhibited stimulating effects and appetite-reducing properties. These characteristics led to its clinical use as an anorectic agent, particularly in Europe during the 1950s. The emergence of 3-Chlorophenmetrazine stems from the exploration of structural modifications to phenmetrazine's molecular framework. By incorporating a chlorine atom into phenmetrazine's structure, researchers aimed to modulate its effects and characteristics.

3-CPM entered the realm of research chemicals and experimental substances. This categorization denotes its classification as a synthetic compound with limited or absent documented medical use. The limited availability of data regarding 3-CPM's pharmacological properties, metabolic processes, and potential risks underscores the importance of employing harm reduction practices for those considering its use. The lack of regulatory oversight also underscores the need for cautious engagement.



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3-Chlorophenmetrazine (3-CPM) is a synthetic compound belonging to the amphetamine family. Amphetamine-class molecules share a phenethylamine core that comprises a phenyl ring connected to an amino (NH2) group through an ethyl chain. An additional methyl substitution is present at the Rα position. These compounds are characterized as alpha-methylated phenethylamines. In the case of 3-CPM, a chlorine atom is introduced at the R3 location of the phenyl ring. A segment of its amphetamine structure is integrated into a morpholine ring. An oxygen group is connected at R2 of the chain, forming a morpholine group by being linked to the terminal amine of the amphetamine chain through an ethyl chain. Notably, 3-CPM is a chlorine-substituted derivative of phenmetrazine.


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Subjective effects

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As such, it is still in progress and may contain incomplete or wrong information.

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Disclaimer: The effects listed below cite the Subjective Effect Index (SEI), an open research literature based on anecdotal user reports and the personal analyses of PsychonautWiki contributors. As a result, they should be viewed with a healthy degree of skepticism.

It is also worth noting that these effects will not necessarily occur in a predictable or reliable manner, although higher doses are more liable to induce the full spectrum of effects. Likewise, adverse effects become increasingly likely with higher doses and may include addiction, severe injury, or death ☠.

Physical effects

Visual effects

Cognitive effects

Auditory effects

Multi-sensory effects

Transpersonal effects

Experience reports

There are currently 0 experience reports which describe the effects of this substance in our experience index.

Additional experience reports can be found here:

Toxicity and harm potential


This toxicity and harm potential section is a stub.

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Note: Always conduct independent research and use harm reduction practices if using this substance.

It is strongly recommended that one use harm reduction practices when using this substance.

Lethal dosage

Tolerance and addiction potential

Dangerous interactions


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Warning: Many psychoactive substances that are reasonably safe to use on their own can suddenly become dangerous and even life-threatening when combined with certain other substances. The following list provides some known dangerous interactions (although it is not guaranteed to include all of them).

Always conduct independent research (e.g. Google, DuckDuckGo, PubMed) to ensure that a combination of two or more substances is safe to consume. Some of the listed interactions have been sourced from TripSit.

Legal status


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See also

External links

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