Buprenorphine/Summary

Main article: Buprenorphine

Psychoactive class: Opioids

Chemical class: Substituted morphinans

Sublingual

• Thresh				Common				Heavy
  0.3	-	1	-	2	-	4	-	8	mg
  		Light				Strong

• • Total: 18 - 24 hours
  • Onset: 40 - 80 minutes
  • Peak: 1.5 - 2 hours
  • Afterglow: 1 - 3 days

Insufflated

• Thresh				Common				Heavy
  0.2	-	0.2	-	0.4	-	0.8	-	1.5	mg
  		Light				Strong

• • Total: 8 - 14 hours
  • Onset: 30 - 60 minutes
  • Peak: 4 - 8 hours
  • Afterglow: 1 - 3 days

Harm potential

• • Moderately addictive with a high potential for abuse
  • Low toxicity

Tolerance

• • Full tolerance is reached develops with prolonged and repeated use
  • Decreases to half after 3 - 7 days
  • Returns to baseline after 1 - 2 weeks
  • Cross-tolerance with all other opioids

Physical effects

• • Appetite suppression
  • Cough suppression
  • Pain relief
  • Respiratory depression
  • Sedation
• • Constipation
  • Decreased heart rate
  • Difficulty urinating
  • Dizziness
  • Itchiness
  • Nausea
  • Respiratory depression

Visual effects

• • Internal hallucination

Cognitive effects

• • Cognitive euphoria
• • Anxiety suppression

See also

• Responsible use
• Summary index
• Subjective effect index
• Psychoactive substance index