Fly agaric: Ibotenic acid decarboxylation to muscimol

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Fly agaric: Ibotenic acid decarboxylation to muscimol
800px-2006-10-25 Amanita muscaria crop.jpg
A. muscaria mushrooms in different stages of growth.
Taxonomical nomenclature
Kingdom Fungi
Phylum Basidiomycota
Class Agaricomycetes
Order Agaricales
Family Amanitaceae
Genus Amanita
Species A. muscaria
Common nomenclature
Common names Fly agaric, Fly amanita
Mycological Characteristics
Spore print White
Constituents
Active constituents Muscimol, Ibotenic acid

This guide will help you to decarboxylate the relatively neurotoxic compound ibotenic acid, to muscimol. Both compounds are found naturally in Amanita muscaria. Heat will also kill larvae.

By method

Oven

  • Heat Amanita muscaria at 200 °F (93°C) for two hours,[1] or 100 °C for 1.5 hour.
  • After decarboxylation, consider drying larger mushrooms fully in room temperature (ideally in a mesh bag to deter flies from laying new eggs) for several days.

Dehydrator

  • Use a dehydrator till Amanita muscaria caps are crispy (at 40 Celsius)
  • Store them for 6-8 weeks for natural decarboxylation (in glass jars preferably).

References