Template:Warning/Nitrous oxide

Nitrous oxide can cause irreversible neurotoxic damages

Frequent and/or chronic use can cause vitamin B₁₂ depletion, such as other rapidly vitamin B₁₂ depleting substance, may lead to severe nerve damage. We recommend that you always supplement with vitamin B12 if you use this substance, regardless dose and frequency to be on the safe side. Especially those with "decreased vitamin B12 absorption, such as in those with small bowel resection, irritable bowel disease, and/or pernicious anemia, and those with reduced intake, such as in vegans and vegetarians". Additionally, improper use puts the user at risk of oxygen deprivation. It is highly advised to use harm reduction practices if using this substance.