Template:SubstanceBox/Baclofen

Chemical Nomenclature

Common names

Baclofen, Lioresal

Substitutive name

β-(4-chlorophenyl)-GABA

Systematic name

5-amino-4-(4-chlorophenyl)-1-hydroxypentan-2-one

Class Membership

Psychoactive class

Depressant

Chemical class

Gabapentinoid

Routes of Administration

WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section.

⇣ Oral
Dosage
Bioavailability	74 %^[1]
Threshold	5 mg
Light	10 - 20 mg
Common	20 - 50 mg
Strong	50 - 100 mg
Heavy	100 mg + Warning: Risk of blackout above 125 mg +
Duration
Total	8 - 14 hours
Onset	30 - 75 minutes
Come up	1 - 1.5 hours
Peak	1 - 2 hours
Offset	1.5 - 2.5 hours
After effects	6 - 12 hours

DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy.

↑ Agarwal, S. K., Kriel, R. L., Cloyd, J. C., Coles, L. D., Scherkenbach, L. A., Tobin, M. H., Krach, L. E. (January 2015). "A pilot study assessing pharmacokinetics and tolerability of oral and intravenous baclofen in healthy adult volunteers". Journal of Child Neurology. 30 (1): 37–41. doi:10.1177/0883073814535504. ISSN 1708-8283.

[Agarwal2015-1] Agarwal, S. K., Kriel, R. L., Cloyd, J. C., Coles, L. D., Scherkenbach, L. A., Tobin, M. H., Krach, L. E. (January 2015). "A pilot study assessing pharmacokinetics and tolerability of oral and intravenous baclofen in healthy adult volunteers". Journal of Child Neurology. 30 (1): 37–41. doi:10.1177/0883073814535504. ISSN 1708-8283.

[1]

Template:SubstanceBox/Baclofen

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