Template:Binding profiles of tropane stimulants

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Transporter binding profiles of tropane stimulants[1][2]
IC50 (nM)
Compound DAT NET SERT
Cocaine 89 ± 4.8 3298 ± 293 1045 ± 89
Dichloropane 0.79 ± 0.09 17.96 ± 0.85 3.13 ± 0.36
Troparil 23 ± 5 920 ± 73 1962 ± 61
  1. ↑ Carroll, F. I., Kotian, P., Dehghani, A., Gray, J. L., Kuzemko, M. A., Parham, K. A., Abraham, P., Lewin, A. H., Boja, J. W., Kuhar, M. J. (January 1995). "Cocaine and 3.beta.-(4'-Substituted phenyl)tropane-2.beta.-carboxylic Acid Ester and Amide Analogs. New High-Affinity and Selective Compounds for the Dopamine Transporter". Journal of Medicinal Chemistry. 38 (2): 379–388. doi:10.1021/jm00002a020. ISSN 0022-2623. 
  2. ↑ Carroll, F. I., Blough, B. E., Nie, Z., Kuhar, M. J., Howell, L. L., Navarro, H. A. (1 April 2005). "Synthesis and Monoamine Transporter Binding Properties of 3β-(3',4'-Disubstituted phenyl)tropane-2β-carboxylic Acid Methyl Esters". Journal of Medicinal Chemistry. 48 (8): 2767–2771. doi:10.1021/jm040185a. ISSN 0022-2623. 
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