Talk:Meclofenoxate
| Summary sheet: Meclofenoxate |
Template:SubstanceBox/Meclofenoxate
Meclofenoxate (meclofenoxate) is a...
Chemistry
Pharmacology
A portion of Meclofenoxate breaks down into DMAE and pCPA. DMAE is then converted to choline.
Subjective effects
Disclaimer: The effects listed below cite the Subjective Effect Index (SEI), an open research literature based on anecdotal user reports and the personal analyses of PsychonautWiki contributors. As a result, they should be viewed with a healthy degree of skepticism.
It is also worth noting that these effects will not necessarily occur in a predictable or reliable manner, although higher doses are more liable to induce the full spectrum of effects. Likewise, adverse effects become increasingly likely with higher doses and may include addiction, severe injury, or death ☠.
Physical effects 
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- Bodily control enhancement
- Body odor alteration - This can be caused in some populations, especially those suffering from trimethylaminuria. Choline (a metabolite of meclofenoxate) is a precursor to trimethylamine, which those with trimethylaminuria are not able to easily break down, oftening resulting in smelling similar to fish.
- Dizziness
- Headaches
- Muscle tension
- Nausea
- Stamina enhancement
- Stimulation - The stimulation which meclofenoxate presents can be considered as primarily subtle and similar to that of caffeine.
- Teeth grinding
Cognitive effects 
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- Anxiolytic
- Depression
- Dream potentiation
- Focus enhancement
- Insomnia
- Memory enhancement
- Mindfulness
- Motivation enhancement
- Wakefulness - In comparison to citicoline, meclofenoxate manifests itself primarily in a physically stimulating manner over a mental stimulation.
Experience reports
There are currently no anecdotal reports which describe the effects of this compound within our experience index. Additional experience reports can be found here:
Toxicity and harm potential
Meclofenoxate is non-addictive, is not known to cause harm, and has an extremely low toxicity relative to dose. Similar to many other nootropic substances, there are relatively few physical side effects associated with acute choline exposure. Various studies have shown that in reasonable doses in a particular context, it presents no negative cognitive, psychiatric or toxic physical consequences of any sort.
Regardless, it is strongly recommended that one is familiar with and uses harm reduction practices when using this substance.
Tolerance and addiction potential
Dangerous interactions
In vitro studies of meclofenoxate showed inhibition of total MAO, MAO A and MAO B in rat brains.[1] Meclofenoxate and MAOIs are a potentially dangerous combination. It is likely that MAOIs could increase the effects of meclofenoxate unpredictably. Taking this chemical while on prescription MAOIs is strongly discouraged.
Legal issues
 |
This legality section is a stub. As such, it may contain incomplete or wrong information. You can help by expanding it. |
- United States - Meclofenoxate is completely legal to purchase in the United States as a dietary supplement.