Experience:10-60mg Cyclazodone, multiple ROAs

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Experience index — SubstanceName Substance(s): Cyclazodone Dose: 10-60+ mg, multiple trials Route of Administration: Oral, Sublingual, Nasal, Rectal, Vaporization Subject Note: Any data is collected for academic research purposes only. We do not sell or store private data (see our general disclaimer). You may share as much or as little personal information as you'd like. If you have any questions or concerns, please email us at team@psy.is.

Age: 38 Sex: F Height: 177cm / 70inches (include both if possible) Weight: 80kg / 176lb (include both if possible) Date: 08/2022 Location: USA Background Note: Extensive experience with many functional and non-functional stims. Includes all classically prescribed -phenidates and amphetamines, several RCs of both families, and novel ones like A-PVP, 3-FPM and Cyclazodone. Uses a baseline of 20mg Adderall XR daily.

Experience report Note: Over the course of a month, I acquired 2g of cyclazodone from an online vendor I had worked with in the past. Previously I had rated it as "nothing to write home about" and gave it to a roommate with a heavier stim tolerance so she'd stop asking me for Adderall.

I tried numerous experiments with it with various ROAs. Here's what I found:

  • It appears to be bioactive via all these ROAs.
  • Most doses were massed on a Gemini-20 mg scale, all except where noted that dosage is unknown.
  • Vaporization seems to be the worst ROA. Does seem compulsive, and tastes caustic and similar to a methylphenidate analog. Significantly more is needed to achieve desired effects and they can last much longer than you want them to if taken too late. The duration of it vaped can still be 5-6 hours and appears dose-dependent, increasing in duration when larger doses are taken.
  • Nasal was my preferred ROA. It did seem to come on somewhat quicker but less noticeable than amphetamines. If I had to guess, it isn't completely bioavailable and some is eliminated to the stomach where it's processed like an oral dose. No scientific data to back it up though.
  • 20mg-30mg seemed to be an ideal insufflated dose for a user with an amphetamine tolerance. Onset within about 5-10m. By subjective feel alone, I'd say it's largely equipotent with Adderall when insufflated at 20mg.
  • Sublingual was performed by putting a known amount of powder onto a piece of nicotine gum, folding the powder into the gum, and chewing. Seemed to work as well as Adderall by this method, would guess the onset is about 10 minutes. Experiments were limited and often the second or third dose of the day; I don't recall how profound the effect was or dosages. More experiments on sublingual ROA will be performed. There was a noticeable increase in stimulation.
  • Oral was my second preferred ROA. Came on gentler and lasted longer. More required for the desired effect, the oral dosing table seems more or less accurate.
  • Rectal dosage was the least common ROA. Due to solubility issues, it's clear some cyclazodone had stuck to the walls of the syringe so I can't be sure about how well it was absorbed. Only attempted once; may attempt to use propylene glycol as a solvent instead for next trials.


More experience reports will be submitted soon, as well as possibly liver enzyme testing.