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Summary sheet: MXiPr
Chemical Nomenclature
Common names MXiPR, MXiP
Substitutive name 3-MeO-2′-Oxo-PCiPr
Systematic name 2-(Isopropylamino)-2-(3-methoxyphenyl)cyclohexanone
Class Membership
Psychoactive class Dissociative
Chemical class Arylcyclohexylamine
Routes of Administration

WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section.

Threshold 5 mg
Light 10 - 20 mg
Common 20 - 40 mg
Strong 40 - 60 mg
Heavy 60 mg +
Total 2 - 5 hours
Onset 20 - 60 minutes
After effects 4 - 48 hours

Threshold 5 mg
Light 10 - 20 mg
Common 20 - 40 mg
Strong 40 - 60 mg
Heavy 60 mg +
Total 1.5 - 4 hours
Onset 2 - 5 minutes
After effects 2 - 12 hours

DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy.

MXiPr (also known as 3-MeO-2′-Oxo-PCiPr and 2-(Isopropylamino)-2-(3-methoxyphenyl)cyclohexanone) is a novel dissociative substance of the arylcyclohexylamine class that produces dissociative and hallucinogenic effects when administered. It is a structural analog of MXE.

MXiPr began to gain popularity in late 2020 [1] and is sold on the online grey area research chemical market as a legal or more readily available to Ketamine or MXE. The initial batch reportedly smelled like pokemon cards, or plastic, and many people allege that it was impure. As the metabolism of precursors can have unpredicted effects, it is strongly recommended to purify this substance yourself. if you suspect that it may be impure and are still keen on taking this substance, at the very least ensure that it to goes through first-pass metabolism by taking it orally.

Anecdotal reports seem to suggest that this drug experiences at least two plateaus. The first plateau at doses around 5-20mg, giving a two hour long experience similar to nitrous oxide, and the second plateau at doses around 20-40+mg giving an experience similar to a K-Hole, with a significantly warmer or "dreamier" afterglow. Little is known if higher plateaus exist, and it is advisable not to push it with this substance as it is extremely under-researched, and can provide a body load after the afterglow wears off, or in lower doses it will give you a mild hangover for 1-2 days.

Very little data exists about the pharmacological properties, metabolism, and toxicity of MXiPr, and it has a very brief history of human usage. It is strongly recommended that one use harm reduction practices if using this substance.

History and culture

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This chemistry section is incomplete.

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MXiPr, or (IUPAC) 2-(3-Methoxyphenyl)-2-[(propan-2-yl)amino]cyclohexan-1-one, is classed as an arylcyclohexylamine drug. Specifically, an Arylcycloalkylamine[2].


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Very little is known about the pharmacology about this substance, however as an arylcyclohexamine it is reasonable to assume that it is an NMDA receptor antagonist. NMDA receptors allow for electrical signals to pass between neurons in the brain and spinal column; for the signals to pass, the receptor must be open. Dissociatives close the NMDA receptors by blocking them. This disconnection of neurons leads to loss of feeling, difficulty moving, and eventually an almost identical equivalent of the famous “k-hole.”

Subjective effects

MXiPr can be said to share similar properties to that of MXE or O-PCE but there have been some anecdotal reports that suggest that this may have a potentially higher risk of inducing:

All of which can most likely be avoided entirely by practicing harm reduction by keeping dosages low, usage infrequent, and avoiding combinations.

This subjective effects section is a stub.

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Disclaimer: The effects listed below cite the Subjective Effect Index (SEI), a research literature based on anecdotal reports and the personal experiences of PsychonautWiki contributors. As a result, they should be regarded with a healthy degree of skepticism. It is worth noting that these effects will not necessarily occur in a predictable or reliable manner, although higher doses are more liable to induce the full spectrum of effects. Likewise, adverse effects become much more likely with higher doses and may include addiction, serious injury, or death.

Physical effects

Visual effects

Cognitive effects

Auditory effects

Disconnective effects

Multi-sensory effects

Experience reports

There are currently 0 experience reports which describe the effects of this substance in our experience index.

Additional experience reports can be found here:

Toxicity and harm potential


This toxicity and harm potential section is a stub.

As such, it may contain incomplete or even dangerously wrong information. You can help by expanding or correcting it.
We also recommend that you conduct independent research and use harm reduction practices when using this substance.

It is strongly recommended that one use harm reduction practices when using this substance.

The toxicity and long-term health effects of recreational MXiPr use do not seem to have been studied in any scientific context and the exact toxic dosage is unknown. This is because MXiPr has very little history of human usage.

Lethal dosage

Tolerance and addiction potential

Urinary tract effects

Regarding its long-term health effects when used repeatedly and over excessive periods, MXiPr seems to exhibit almost identical bladder and urinary tract problems to those found within ketamine, but to a lesser extent. This is because MXiPr is far more potent than ketamine, so significantly less of drug needs to be consumed. Symptoms of ketamine-induced cystitis can become severe and can be described as:

  • Urinary frequency - Urinary frequency is the need to empty the bladder every few minutes.
  • Urinary urgency - This can be described as a sudden, compelling need to urinate.
  • Urinary pressure - This is experienced as a constant sensation of fullness in the bladder that is unrelieved by urination.
  • Pelvic and bladder pain - Pain can develop suddenly and severely, especially since the bladder fills with urine.
  • Hematuria - Hematuria is visible blood in the urine.
  • Incontinence - This is the leakage of urine.

All of these, however, can easily be avoided by simply not using MXiPr on a daily or even weekly basis and consciously limiting one's usage of the substance.

Dangerous interactions


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Although many psychoactive substances are reasonably safe to use on their own, they can suddenly become dangerous or even life-threatening when combined with other substances. The following list includes some known dangerous combinations (although it is not guaranteed to include all of them). Independent research (e.g. Google, DuckDuckGo) should always be conducted to ensure that a combination of two or more substances is safe to consume. Some of the listed interactions have been sourced from TripSit.

  • Stimulants - Both stimulants and dissociatives carry the risk of adverse psychological reactions like anxiety, mania, delusions and psychosis and these risks are exacerbated when the two substances are combined.
  • Depressants - Because both depress the respiratory system, this combination can result in an increased risk of suddenly falling unconscious, vomiting and choking to death from the resulting suffocation. If nausea or vomiting occurs, users should attempt to fall asleep in the recovery position or have a friend move them into it.

Legal status


This legality section is a stub.

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See also

External links

Bluelight - The Big & Dandy 3-MeO-2′-oxo-PCiPr (MXiPr) Thread


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